Molecular genetic and biochemical profiles of malignant neoplasms during pregnancy

The article presents a review of modern literature data on molecular-genetic and biochemical profiles of malignant tumors of varying locations. It is shown that molecular-genetic and transcription profiles of pregnancy-associated malignant tumors are systems consisting of various components, many of...

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Main Authors: A. L. Chernyshova, A. A. Chernyakov, Yu. M. Truschuk, N. V. Yunusova, N. V. Sevostyanova, Ya. I. Arkhipova, O. S. Dil, A. E. Chernyshova
Format: Article
Language:Russian
Published: ABV-press 2024-10-01
Series:Успехи молекулярной онкологии
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Online Access:https://umo.abvpress.ru/jour/article/view/706
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author A. L. Chernyshova
A. A. Chernyakov
Yu. M. Truschuk
N. V. Yunusova
N. V. Sevostyanova
Ya. I. Arkhipova
O. S. Dil
A. E. Chernyshova
author_facet A. L. Chernyshova
A. A. Chernyakov
Yu. M. Truschuk
N. V. Yunusova
N. V. Sevostyanova
Ya. I. Arkhipova
O. S. Dil
A. E. Chernyshova
author_sort A. L. Chernyshova
collection DOAJ
description The article presents a review of modern literature data on molecular-genetic and biochemical profiles of malignant tumors of varying locations. It is shown that molecular-genetic and transcription profiles of pregnancy-associated malignant tumors are systems consisting of various components, many of which remain poorly researched. Additionally, morphological and biochemical characteristics of the placenta and tumor tissue are discussed. In the recent years, individual researchers and research groups have demonstrated heightened interests in this problem which undoubtedly soon will lead to a deeper and stronger understanding of mechanisms of progression and metastasis of oncological diseases during pregnancy. The knowledge of the principles of normal embryogenesis as a process of intrauterine development of a fetus, as well as investigation of molecular basis of pathogenesis of spontaneous abortion will undoubtedly help in determination of new targets and development of new therapeutical molecules for cancer treatment.
format Article
id doaj-art-29c3e238fd704e09994b578dad614cf1
institution Kabale University
issn 2313-805X
2413-3787
language Russian
publishDate 2024-10-01
publisher ABV-press
record_format Article
series Успехи молекулярной онкологии
spelling doaj-art-29c3e238fd704e09994b578dad614cf12025-08-20T03:38:02ZrusABV-pressУспехи молекулярной онкологии2313-805X2413-37872024-10-01113324010.17650/2313-805X-2024-11-3-32-40337Molecular genetic and biochemical profiles of malignant neoplasms during pregnancyA. L. Chernyshova0A. A. Chernyakov1Yu. M. Truschuk2N. V. Yunusova3N. V. Sevostyanova4Ya. I. Arkhipova5O. S. Dil6A. E. Chernyshova7E.N. Meshalkin National Medical Center, Ministry of Health of Russia; Novosibirsk State Medical University, Ministry of Health of RussiaScientific Research Institute of Oncology, Tomsk National Medical Research Center, Russian Academy of SciencesScientific Research Institute of Oncology, Tomsk National Medical Research Center, Russian Academy of SciencesScientific Research Institute of Oncology, Tomsk National Medical Research Center, Russian Academy of Sciences; Siberian State Medical University, Ministry of Health of RussiaSiberian State Medical University, Ministry of Health of RussiaSiberian State Medical University, Ministry of Health of RussiaE.N. Meshalkin National Medical Center, Ministry of Health of RussiaSaint-Petersburg State UniversityThe article presents a review of modern literature data on molecular-genetic and biochemical profiles of malignant tumors of varying locations. It is shown that molecular-genetic and transcription profiles of pregnancy-associated malignant tumors are systems consisting of various components, many of which remain poorly researched. Additionally, morphological and biochemical characteristics of the placenta and tumor tissue are discussed. In the recent years, individual researchers and research groups have demonstrated heightened interests in this problem which undoubtedly soon will lead to a deeper and stronger understanding of mechanisms of progression and metastasis of oncological diseases during pregnancy. The knowledge of the principles of normal embryogenesis as a process of intrauterine development of a fetus, as well as investigation of molecular basis of pathogenesis of spontaneous abortion will undoubtedly help in determination of new targets and development of new therapeutical molecules for cancer treatment.https://umo.abvpress.ru/jour/article/view/706cancerpregnancyplacentamolecular genetic factorbiochemical markerprognosiss
spellingShingle A. L. Chernyshova
A. A. Chernyakov
Yu. M. Truschuk
N. V. Yunusova
N. V. Sevostyanova
Ya. I. Arkhipova
O. S. Dil
A. E. Chernyshova
Molecular genetic and biochemical profiles of malignant neoplasms during pregnancy
Успехи молекулярной онкологии
cancer
pregnancy
placenta
molecular genetic factor
biochemical marker
prognosiss
title Molecular genetic and biochemical profiles of malignant neoplasms during pregnancy
title_full Molecular genetic and biochemical profiles of malignant neoplasms during pregnancy
title_fullStr Molecular genetic and biochemical profiles of malignant neoplasms during pregnancy
title_full_unstemmed Molecular genetic and biochemical profiles of malignant neoplasms during pregnancy
title_short Molecular genetic and biochemical profiles of malignant neoplasms during pregnancy
title_sort molecular genetic and biochemical profiles of malignant neoplasms during pregnancy
topic cancer
pregnancy
placenta
molecular genetic factor
biochemical marker
prognosiss
url https://umo.abvpress.ru/jour/article/view/706
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AT nvyunusova moleculargeneticandbiochemicalprofilesofmalignantneoplasmsduringpregnancy
AT nvsevostyanova moleculargeneticandbiochemicalprofilesofmalignantneoplasmsduringpregnancy
AT yaiarkhipova moleculargeneticandbiochemicalprofilesofmalignantneoplasmsduringpregnancy
AT osdil moleculargeneticandbiochemicalprofilesofmalignantneoplasmsduringpregnancy
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