Brivaracetam and rufinamide combination increased seizure threshold and improved neurobehavioral deficits in corneal kindling model of epilepsy

Brivaracetam and rufinamide combination increased seizure threshold and improved neurobehavioral deficits in corneal kindling model of epilepsy

Abstract Background Besides seizures, a myriad of overlapping neuropsychiatric and cognitive comorbidities occur in patients with epilepsy, which further debilitates their quality of life. This study provides an in‐depth characterization of the impact of brivaracetam and rufinamide individually and...

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Bibliographic Details
Main Authors:	Awais Sattar, Zohabia Rehman, Hammad Murtaza, Waseem Ashraf, Tanveer Ahmad, Faleh Alqahtani, Imran Imran
Format:	Article
Language:	English
Published:	Wiley 2025-02-01
Series:	Animal Models and Experimental Medicine
Subjects:	brivaracetam corneal kindling epilepsy neurobehavioral analyses oxidative stress rufinamide
Online Access:	https://doi.org/10.1002/ame2.12478
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