Metabolic evaluation and medical management of staghorn calculi
Staghorn renal calculi are large renal calculi that occupy nearly the entirety of the renal collecting system. They may be composed of metabolic or infection stone types. They are often associated with specific metabolic defects. Infection stones are associated with urease-producing bacterial urinar...
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| Format: | Article |
| Language: | English |
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Elsevier
2020-04-01
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| Series: | Asian Journal of Urology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214388219301237 |
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| author | Russell S. Terry Glenn M. Preminger |
| author_facet | Russell S. Terry Glenn M. Preminger |
| author_sort | Russell S. Terry |
| collection | DOAJ |
| description | Staghorn renal calculi are large renal calculi that occupy nearly the entirety of the renal collecting system. They may be composed of metabolic or infection stone types. They are often associated with specific metabolic defects. Infection stones are associated with urease-producing bacterial urinary tract infections. The ideal treatment for staghorn calculi is maximal surgical removal. However, some patients are either unwilling or unable to proceed with that modality of treatment, and therefore other management must be used. One such technique is the metabolic evaluation with directed medical management. Based on contemporary evidence that the majority of staghorn stones are metabolic in etiology, and furthermore that even infection stones are usually associated with metabolic abnormalities, metabolic evaluation with directed medical management is recommended for all staghorn stone formers. The scientific basis of this recommendation is reviewed in the present work. Keywords: Urolithiasis, Staghorn, Metabolic evaluation, Struvite |
| format | Article |
| id | doaj-art-29bb52c9ca6e4cccb0152b264664920f |
| institution | Kabale University |
| issn | 2214-3882 |
| language | English |
| publishDate | 2020-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Asian Journal of Urology |
| spelling | doaj-art-29bb52c9ca6e4cccb0152b264664920f2025-08-20T03:49:04ZengElsevierAsian Journal of Urology2214-38822020-04-017212212910.1016/j.ajur.2019.12.007Metabolic evaluation and medical management of staghorn calculiRussell S. Terry0Glenn M. Preminger1Duke Comprehensive Kidney Stone Center, Division of Urologic Surgery, Duke University Medical Center, Durham, NC, USACorresponding author.; Duke Comprehensive Kidney Stone Center, Division of Urologic Surgery, Duke University Medical Center, Durham, NC, USAStaghorn renal calculi are large renal calculi that occupy nearly the entirety of the renal collecting system. They may be composed of metabolic or infection stone types. They are often associated with specific metabolic defects. Infection stones are associated with urease-producing bacterial urinary tract infections. The ideal treatment for staghorn calculi is maximal surgical removal. However, some patients are either unwilling or unable to proceed with that modality of treatment, and therefore other management must be used. One such technique is the metabolic evaluation with directed medical management. Based on contemporary evidence that the majority of staghorn stones are metabolic in etiology, and furthermore that even infection stones are usually associated with metabolic abnormalities, metabolic evaluation with directed medical management is recommended for all staghorn stone formers. The scientific basis of this recommendation is reviewed in the present work. Keywords: Urolithiasis, Staghorn, Metabolic evaluation, Struvitehttp://www.sciencedirect.com/science/article/pii/S2214388219301237 |
| spellingShingle | Russell S. Terry Glenn M. Preminger Metabolic evaluation and medical management of staghorn calculi Asian Journal of Urology |
| title | Metabolic evaluation and medical management of staghorn calculi |
| title_full | Metabolic evaluation and medical management of staghorn calculi |
| title_fullStr | Metabolic evaluation and medical management of staghorn calculi |
| title_full_unstemmed | Metabolic evaluation and medical management of staghorn calculi |
| title_short | Metabolic evaluation and medical management of staghorn calculi |
| title_sort | metabolic evaluation and medical management of staghorn calculi |
| url | http://www.sciencedirect.com/science/article/pii/S2214388219301237 |
| work_keys_str_mv | AT russellsterry metabolicevaluationandmedicalmanagementofstaghorncalculi AT glennmpreminger metabolicevaluationandmedicalmanagementofstaghorncalculi |