In Lower‐Grade Gliomas, the SPARC Family Exacerbates Prognosis by Influencing Immunity, Stemness, and Metabolism

In Lower‐Grade Gliomas, the SPARC Family Exacerbates Prognosis by Influencing Immunity, Stemness, and Metabolism

ABSTRACT Background Involvement of the SPARC stromal protein family in crucial biological regulatory mechanisms is well‐documented. But understanding the consequences of imbalanced SPARC protein activity in lower‐grade glioma (LGG) is still emerging. Aims Examining the clinical significance of SPARC...

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Bibliographic Details
Main Authors: Qiaoying Peng, Wenxia Zhou, Ying Chen, Yong Cai
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Cancer Reports
Subjects:
EMT
GSC
LGG
methylation
SPARC
Online Access:https://doi.org/10.1002/cnr2.70307
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