Computational analysis of whole slide images predicts PD-L1 expression and progression-free survival in immunotherapy-treated non-small cell lung cancer patients

Computational analysis of whole slide images predicts PD-L1 expression and progression-free survival in immunotherapy-treated non-small cell lung cancer patients

Abstract Background Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by significantly improving the efficacy of treatments and tolerability for patients with non-small cell lung cancer (NSCLC). However, even after meticulous selection based on molecular criteria, only 20–30%...

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Main Authors: Abdou Khadir Dia, Alona Kolnohuz, Sevinj Yolchuyeva, Marion Tonneau, Fabien Lamaze, Michele Orain, Andréanne Gagné, Florence Blais, François Coulombe, Julie Malo, Wiam Belkaid, Arielle Elkrief, Drew Williamson, Bertrand Routy, Philippe Joubert, Mathieu Laplante, Steve Bilodeau, Venkata SK. Manem
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Translational Medicine
Online Access:https://doi.org/10.1186/s12967-025-06487-2
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