Immuno-haematological impact of Eimeria tenella infection on broilers vaccinated with infectious bursal disease and Newcastle disease vaccines
Abstract Background Eimeria infection of poultry species is one of the famous parasitic diseases, Eimeria tenella is the most prevalent one in the field. This article aims to know the immune-haematological effect of E. tenella as a stress factor in birds vaccinated with Newcastle disease and IBD vac...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2025-06-01
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| Series: | Beni-Suef University Journal of Basic and Applied Sciences |
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| Online Access: | https://doi.org/10.1186/s43088-025-00651-9 |
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| author | Mohammed A. Gamaleldin Al-Hassan Mohammed Mostafa Basem R. Nageib |
| author_facet | Mohammed A. Gamaleldin Al-Hassan Mohammed Mostafa Basem R. Nageib |
| author_sort | Mohammed A. Gamaleldin |
| collection | DOAJ |
| description | Abstract Background Eimeria infection of poultry species is one of the famous parasitic diseases, Eimeria tenella is the most prevalent one in the field. This article aims to know the immune-haematological effect of E. tenella as a stress factor in birds vaccinated with Newcastle disease and IBD vaccine. For this study, fifty one-day-old broilers were used and divided into five groups: group A is control (non-vaccinated non-infected birds), group B was infected with E. tenella and vaccinated with Lasota vaccine, group C was infected with E. tenella parasite and vaccinated with IBD intermediate plus vaccine, group D was non-infected and vaccinated with Lasota vaccine, and group E was non-infected and vaccinated with IBD intermediate plus vaccine. Different parameters like oocyst count, body weight (BW), and vaccinal titer were estimated and in addition, erythrogram, leukogram, protein carbonyl (PC), superoxide dismutase (SOD), and interleukin 1β (IL1β) levels were also evaluated. Results The infected groups were characterized by a remarkable alteration in oocysts count and a noticeable reduction in BW, vaccinal titers, SOD, and IL1β. In addition, high PC, with marked anemia, leukocytopenia, and lymphocytosis were seen in infected groups. While, normal BW, increasable SOD, and IL1β levels along with, leukocytosis and lymphocytosis were prominent changes in vaccinated groups only. Conclusion The coccidian infection has adverse effects on healthy performance parameters including body weight, haematological, immune profiles, and ND and IBD vaccination. |
| format | Article |
| id | doaj-art-29b119cffd2a4701bc743c8bc88daeaa |
| institution | OA Journals |
| issn | 2314-8543 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Beni-Suef University Journal of Basic and Applied Sciences |
| spelling | doaj-art-29b119cffd2a4701bc743c8bc88daeaa2025-08-20T02:05:39ZengSpringerOpenBeni-Suef University Journal of Basic and Applied Sciences2314-85432025-06-0114111010.1186/s43088-025-00651-9Immuno-haematological impact of Eimeria tenella infection on broilers vaccinated with infectious bursal disease and Newcastle disease vaccinesMohammed A. Gamaleldin0Al-Hassan Mohammed Mostafa1Basem R. Nageib2Department of Poultry disease, Animal Health Research Institute, Agricultural Research CenterDepartment of Paathology and Clinical Pathology, Animal Health Research Institute, Agricultural Research CenterDepartment of Parasitology, Animal Health Research Institute, Agricultural Research CenterAbstract Background Eimeria infection of poultry species is one of the famous parasitic diseases, Eimeria tenella is the most prevalent one in the field. This article aims to know the immune-haematological effect of E. tenella as a stress factor in birds vaccinated with Newcastle disease and IBD vaccine. For this study, fifty one-day-old broilers were used and divided into five groups: group A is control (non-vaccinated non-infected birds), group B was infected with E. tenella and vaccinated with Lasota vaccine, group C was infected with E. tenella parasite and vaccinated with IBD intermediate plus vaccine, group D was non-infected and vaccinated with Lasota vaccine, and group E was non-infected and vaccinated with IBD intermediate plus vaccine. Different parameters like oocyst count, body weight (BW), and vaccinal titer were estimated and in addition, erythrogram, leukogram, protein carbonyl (PC), superoxide dismutase (SOD), and interleukin 1β (IL1β) levels were also evaluated. Results The infected groups were characterized by a remarkable alteration in oocysts count and a noticeable reduction in BW, vaccinal titers, SOD, and IL1β. In addition, high PC, with marked anemia, leukocytopenia, and lymphocytosis were seen in infected groups. While, normal BW, increasable SOD, and IL1β levels along with, leukocytosis and lymphocytosis were prominent changes in vaccinated groups only. Conclusion The coccidian infection has adverse effects on healthy performance parameters including body weight, haematological, immune profiles, and ND and IBD vaccination.https://doi.org/10.1186/s43088-025-00651-9BroilerEimeria tenellaND vaccineAnemiaProtein carbonylInterleukin 1β |
| spellingShingle | Mohammed A. Gamaleldin Al-Hassan Mohammed Mostafa Basem R. Nageib Immuno-haematological impact of Eimeria tenella infection on broilers vaccinated with infectious bursal disease and Newcastle disease vaccines Beni-Suef University Journal of Basic and Applied Sciences Broiler Eimeria tenella ND vaccine Anemia Protein carbonyl Interleukin 1β |
| title | Immuno-haematological impact of Eimeria tenella infection on broilers vaccinated with infectious bursal disease and Newcastle disease vaccines |
| title_full | Immuno-haematological impact of Eimeria tenella infection on broilers vaccinated with infectious bursal disease and Newcastle disease vaccines |
| title_fullStr | Immuno-haematological impact of Eimeria tenella infection on broilers vaccinated with infectious bursal disease and Newcastle disease vaccines |
| title_full_unstemmed | Immuno-haematological impact of Eimeria tenella infection on broilers vaccinated with infectious bursal disease and Newcastle disease vaccines |
| title_short | Immuno-haematological impact of Eimeria tenella infection on broilers vaccinated with infectious bursal disease and Newcastle disease vaccines |
| title_sort | immuno haematological impact of eimeria tenella infection on broilers vaccinated with infectious bursal disease and newcastle disease vaccines |
| topic | Broiler Eimeria tenella ND vaccine Anemia Protein carbonyl Interleukin 1β |
| url | https://doi.org/10.1186/s43088-025-00651-9 |
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