Transarterial Chemoembolization of Metastatic Liver Lesions in Patients with Colorectal Cancer
Aim. To evaluate the efficacy of transarterial chemoembolization in patients with metastases of colorectal cancer in the liver.Materials and methods. A study aimed at investigating the effect of selective transarterial chemoembolization (TACE) of the hepatic artery on liver metastases in colorectal...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2019-12-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/419 |
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| _version_ | 1823860115284951040 |
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| author | O. Yu. Stukalova G. P. Gens Z. Kh. Shugushev V. V. Maslov A. G. Chepurnoy |
| author_facet | O. Yu. Stukalova G. P. Gens Z. Kh. Shugushev V. V. Maslov A. G. Chepurnoy |
| author_sort | O. Yu. Stukalova |
| collection | DOAJ |
| description | Aim. To evaluate the efficacy of transarterial chemoembolization in patients with metastases of colorectal cancer in the liver.Materials and methods. A study aimed at investigating the effect of selective transarterial chemoembolization (TACE) of the hepatic artery on liver metastases in colorectal cancer was conducted at the Oncology Centre of the RZhD Central Clinical Hospital No. 2 named after N.A. Semashko, Moscow. The research basis included data for 10 patients, who had undergone chemoembolization of the hepatic arteries using Biosphere microspheres 50– 100 µm — 25 mg and doxorubicin 50 mg.Results. Both immediate and long-term results of up to 12 months were evaluated using the RECIST 1.1 scale. A partial response was achieved after 4 TACE treatments in 22.2 % of cases. The stabilization of the oncological process in the liver was observed after 9 TACE treatments in 50 % of cases. Disease progression was noted after 5 procedures in 27.8 % of cases.Conclusions. Transarterial chemoembolization of metastatic liver lesions in patients with colorectal cancer can be used according to certain indications in specialized centres providing endovascular treatment services. |
| format | Article |
| id | doaj-art-29b07fc0d6054764b96bd09a2d02f270 |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2019-12-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-29b07fc0d6054764b96bd09a2d02f2702025-02-10T16:14:35ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732019-12-01295364210.22416/1382-4376-2019-29-5-36-42327Transarterial Chemoembolization of Metastatic Liver Lesions in Patients with Colorectal CancerO. Yu. Stukalova0G. P. Gens1Z. Kh. Shugushev2V. V. Maslov3A. G. Chepurnoy4A.I. Yevdokimov Moscow State University of Medicine and Dentistry; RZhD Central Clinical Hospital No. 2 named after N.A. SemashkoA.I. Yevdokimov Moscow State University of Medicine and DentistryRZhD Central Clinical Hospital No. 2 named after N.A. SemashkoRZhD Central Clinical Hospital No. 2 named after N.A. SemashkoRZhD Central Clinical Hospital No. 2 named after N.A. SemashkoAim. To evaluate the efficacy of transarterial chemoembolization in patients with metastases of colorectal cancer in the liver.Materials and methods. A study aimed at investigating the effect of selective transarterial chemoembolization (TACE) of the hepatic artery on liver metastases in colorectal cancer was conducted at the Oncology Centre of the RZhD Central Clinical Hospital No. 2 named after N.A. Semashko, Moscow. The research basis included data for 10 patients, who had undergone chemoembolization of the hepatic arteries using Biosphere microspheres 50– 100 µm — 25 mg and doxorubicin 50 mg.Results. Both immediate and long-term results of up to 12 months were evaluated using the RECIST 1.1 scale. A partial response was achieved after 4 TACE treatments in 22.2 % of cases. The stabilization of the oncological process in the liver was observed after 9 TACE treatments in 50 % of cases. Disease progression was noted after 5 procedures in 27.8 % of cases.Conclusions. Transarterial chemoembolization of metastatic liver lesions in patients with colorectal cancer can be used according to certain indications in specialized centres providing endovascular treatment services.https://www.gastro-j.ru/jour/article/view/419chemoembolizationcolorectal cancerliver metastasescolon cancerrectal cancer |
| spellingShingle | O. Yu. Stukalova G. P. Gens Z. Kh. Shugushev V. V. Maslov A. G. Chepurnoy Transarterial Chemoembolization of Metastatic Liver Lesions in Patients with Colorectal Cancer Российский журнал гастроэнтерологии, гепатологии, колопроктологии chemoembolization colorectal cancer liver metastases colon cancer rectal cancer |
| title | Transarterial Chemoembolization of Metastatic Liver Lesions in Patients with Colorectal Cancer |
| title_full | Transarterial Chemoembolization of Metastatic Liver Lesions in Patients with Colorectal Cancer |
| title_fullStr | Transarterial Chemoembolization of Metastatic Liver Lesions in Patients with Colorectal Cancer |
| title_full_unstemmed | Transarterial Chemoembolization of Metastatic Liver Lesions in Patients with Colorectal Cancer |
| title_short | Transarterial Chemoembolization of Metastatic Liver Lesions in Patients with Colorectal Cancer |
| title_sort | transarterial chemoembolization of metastatic liver lesions in patients with colorectal cancer |
| topic | chemoembolization colorectal cancer liver metastases colon cancer rectal cancer |
| url | https://www.gastro-j.ru/jour/article/view/419 |
| work_keys_str_mv | AT oyustukalova transarterialchemoembolizationofmetastaticliverlesionsinpatientswithcolorectalcancer AT gpgens transarterialchemoembolizationofmetastaticliverlesionsinpatientswithcolorectalcancer AT zkhshugushev transarterialchemoembolizationofmetastaticliverlesionsinpatientswithcolorectalcancer AT vvmaslov transarterialchemoembolizationofmetastaticliverlesionsinpatientswithcolorectalcancer AT agchepurnoy transarterialchemoembolizationofmetastaticliverlesionsinpatientswithcolorectalcancer |