Therapeutic effects and potential mechanisms of astragaloside IV on pulmonary fibrosis: a systematic review and meta-analysis of preclinical studies

Therapeutic effects and potential mechanisms of astragaloside IV on pulmonary fibrosis: a systematic review and meta-analysis of preclinical studies

BackgroundPulmonary fibrosis (PF) remains a devastating disease with limited therapeutic options. Astragaloside IV (AS-IV), a natural compound from Astragalus mongholicus (AM), has shown promise as a possible treatment for fibrosis. However, a systematic evaluation of its therapeutic efficacy and un...

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Bibliographic Details
Main Authors: Shujuan Zhang, Yan Xue, Xing Zhang, Feng Chen, Yalan Li, Wei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
Astragalus mongholicus
astragaloside IV
animal model
pulmonary fibrosis
meta-analysis
systematic review
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1564290/full
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