Reduction in Door-to-Needle Time after Transfer of Thrombolysis Site from CCU to Emergency Department

Objective. Early restoration of coronary perfusion by thrombolysis or percutaneous coronary intervention is the main modality of treatment to salvage the ischemic myocardium. The earlier the procedure is completed, the greater the benefit is in saving myocardium and restoring its functions. The aim...

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Main Authors: Osama Mohammed, Firjith C. Paramba, Naushad V. Aboobaker, Riyadh A. Mohammed, Nishan K. Purayil, Haitham M. Jassim, Mohammad K. Shariff, Saud M. Aslam, Farook F. Muhsen, Khalid H. Al Noor, Hani H. Al Kilani
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Emergency Medicine International
Online Access:http://dx.doi.org/10.1155/2013/208271
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author Osama Mohammed
Firjith C. Paramba
Naushad V. Aboobaker
Riyadh A. Mohammed
Nishan K. Purayil
Haitham M. Jassim
Mohammad K. Shariff
Saud M. Aslam
Farook F. Muhsen
Khalid H. Al Noor
Hani H. Al Kilani
author_facet Osama Mohammed
Firjith C. Paramba
Naushad V. Aboobaker
Riyadh A. Mohammed
Nishan K. Purayil
Haitham M. Jassim
Mohammad K. Shariff
Saud M. Aslam
Farook F. Muhsen
Khalid H. Al Noor
Hani H. Al Kilani
author_sort Osama Mohammed
collection DOAJ
description Objective. Early restoration of coronary perfusion by thrombolysis or percutaneous coronary intervention is the main modality of treatment to salvage the ischemic myocardium. The earlier the procedure is completed, the greater the benefit is in saving myocardium and restoring its functions. The aim of the study is to compare the door-to-needle time (DNT) in acute ST elevation myocardial infarction (STEMI) in the period prior to December 2008 when the site of thrombolysis was in coronary care unit (CCU) and the period after that when the site was shifted to emergency department (ED). Methods. A retrospective, descriptive study was conducted at Al Khor Hospital, Qatar, in patients with acute STEMI who underwent thrombolysis at CCU and ED from April 2005 until December 2011, to compare the DNT, duration of hospitalization, and mortality. Results. A total of 211 patients with acute STEMI were eligible for thrombolysis; 58 patients were thrombolysed in the CCU and 153 in ED. The median DNT was reduced from 33.5 minutes in the CCU to 17 minutes in the ED representing a reduction of more than 50% with a P value of < 0.0001. Conclusion. The transfer of the thrombolysis site from CCU to the ED was associated with a dramatic and significant reduction in median door-to-needle time by more than half.
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spelling doaj-art-29a45fac342940ae93effa6e25d4d11e2025-08-20T02:04:00ZengWileyEmergency Medicine International2090-28402090-28592013-01-01201310.1155/2013/208271208271Reduction in Door-to-Needle Time after Transfer of Thrombolysis Site from CCU to Emergency DepartmentOsama Mohammed0Firjith C. Paramba1Naushad V. Aboobaker2Riyadh A. Mohammed3Nishan K. Purayil4Haitham M. Jassim5Mohammad K. Shariff6Saud M. Aslam7Farook F. Muhsen8Khalid H. Al Noor9Hani H. Al Kilani10Department of Emergency Medicine, Al Khor Hospital, Hamad Medical Corporation, P.O. Box 21086, Doha, QatarDepartment of Emergency Medicine, Al Khor Hospital, Hamad Medical Corporation, P.O. Box 21086, Doha, QatarDepartment of Emergency Medicine, Al Khor Hospital, Hamad Medical Corporation, P.O. Box 21086, Doha, QatarDepartment of Emergency Medicine, Al Khor Hospital, Hamad Medical Corporation, P.O. Box 21086, Doha, QatarDepartment of Emergency Medicine, Al Khor Hospital, Hamad Medical Corporation, P.O. Box 21086, Doha, QatarDepartment of Emergency Medicine, Al Khor Hospital, Hamad Medical Corporation, P.O. Box 21086, Doha, QatarDepartment of Emergency Medicine, Al Khor Hospital, Hamad Medical Corporation, P.O. Box 21086, Doha, QatarDepartment of Emergency Medicine, Al Khor Hospital, Hamad Medical Corporation, P.O. Box 21086, Doha, QatarDepartment of Emergency Medicine, Al Khor Hospital, Hamad Medical Corporation, P.O. Box 21086, Doha, QatarDepartment of Emergency Medicine, Al Khor Hospital, Hamad Medical Corporation, P.O. Box 21086, Doha, QatarDepartment of Emergency Medicine, Al Khor Hospital, Hamad Medical Corporation, P.O. Box 21086, Doha, QatarObjective. Early restoration of coronary perfusion by thrombolysis or percutaneous coronary intervention is the main modality of treatment to salvage the ischemic myocardium. The earlier the procedure is completed, the greater the benefit is in saving myocardium and restoring its functions. The aim of the study is to compare the door-to-needle time (DNT) in acute ST elevation myocardial infarction (STEMI) in the period prior to December 2008 when the site of thrombolysis was in coronary care unit (CCU) and the period after that when the site was shifted to emergency department (ED). Methods. A retrospective, descriptive study was conducted at Al Khor Hospital, Qatar, in patients with acute STEMI who underwent thrombolysis at CCU and ED from April 2005 until December 2011, to compare the DNT, duration of hospitalization, and mortality. Results. A total of 211 patients with acute STEMI were eligible for thrombolysis; 58 patients were thrombolysed in the CCU and 153 in ED. The median DNT was reduced from 33.5 minutes in the CCU to 17 minutes in the ED representing a reduction of more than 50% with a P value of < 0.0001. Conclusion. The transfer of the thrombolysis site from CCU to the ED was associated with a dramatic and significant reduction in median door-to-needle time by more than half.http://dx.doi.org/10.1155/2013/208271
spellingShingle Osama Mohammed
Firjith C. Paramba
Naushad V. Aboobaker
Riyadh A. Mohammed
Nishan K. Purayil
Haitham M. Jassim
Mohammad K. Shariff
Saud M. Aslam
Farook F. Muhsen
Khalid H. Al Noor
Hani H. Al Kilani
Reduction in Door-to-Needle Time after Transfer of Thrombolysis Site from CCU to Emergency Department
Emergency Medicine International
title Reduction in Door-to-Needle Time after Transfer of Thrombolysis Site from CCU to Emergency Department
title_full Reduction in Door-to-Needle Time after Transfer of Thrombolysis Site from CCU to Emergency Department
title_fullStr Reduction in Door-to-Needle Time after Transfer of Thrombolysis Site from CCU to Emergency Department
title_full_unstemmed Reduction in Door-to-Needle Time after Transfer of Thrombolysis Site from CCU to Emergency Department
title_short Reduction in Door-to-Needle Time after Transfer of Thrombolysis Site from CCU to Emergency Department
title_sort reduction in door to needle time after transfer of thrombolysis site from ccu to emergency department
url http://dx.doi.org/10.1155/2013/208271
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