Exogenous acetylsalicylic acid mitigates cold stress in common bean seedlings by enhancing antioxidant defense and photosynthetic efficiency

Cold stress severely limits the growth and productivity of common bean (Phaseolus vulgaris L.) seedlings, particularly during early development. Exogenous application of acetylsalicylic acid (ASA) has proven to be an effective strategy for enhancing cold tolerance. This study investigates the useful...

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Main Authors: Barkat Ali, Sujon Kumar, Xiyu Sui, Jianpo Niu, Junqi Yang, Mengni Zheng, Yi Tang, Huanxiu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Plant Science
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Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2025.1589706/full
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author Barkat Ali
Sujon Kumar
Xiyu Sui
Jianpo Niu
Junqi Yang
Mengni Zheng
Yi Tang
Huanxiu Li
author_facet Barkat Ali
Sujon Kumar
Xiyu Sui
Jianpo Niu
Junqi Yang
Mengni Zheng
Yi Tang
Huanxiu Li
author_sort Barkat Ali
collection DOAJ
description Cold stress severely limits the growth and productivity of common bean (Phaseolus vulgaris L.) seedlings, particularly during early development. Exogenous application of acetylsalicylic acid (ASA) has proven to be an effective strategy for enhancing cold tolerance. This study investigates the usefulness of exogenous ASA in enhancing cold tolerance in common bean seedlings exposed to cold stress of 5°C for 12 and 24 hours, along with a control (0h). ASA treatments (1 mM and 2 mM) significantly improved critical physiological and biochemical parameters, including photosynthesis, chlorophyll and carotenoid concentrations, oxidative stress markers, malondialdehyde, electrical conductivity, total soluble proteins (MDA, EC, SP), and antioxidant enzyme activity. Under cold stress, ASA2 constantly outperformed the other treatments. Following a 12-hour period, ASA2 showed increased chlorophyll concentrations (8.88%) and augmented Chl a levels (21.25%), alongside reducing MDA by 24.96% and SP by 67.1%. After 24 h, ASA2 demonstrated a slight increase in chlorophyll (4.26%) and raised Chl a (25.33%), with a significant reduction in MDA (16.5%) and SP (68.3%). ASA1 showed enhancements, mainly in Chl b (39.89% at 12 h) and antioxidant enzymes, with notable increases in SOD (113.17% at 12 h) and POD (110.98% at 12 h). Correlation studies indicated significant positive relationships between antioxidant enzyme activity such as, superoxide dismutase, catalase, peroxidase, ascorbate peroxidase (SOD, CAT, POD, and APX) and photosynthetic efficiency. Principal component analysis (PCA) identified ASA2 as the most effective treatment for enhancing stress resilience, accounting for the largest variance in membrane integrity and reduction of oxidative stress. Network analysis further confirmed that ASA2 strengthened the connections between photosynthesis and antioxidant activity, with more resilient and interconnected nodes indicating improved stress adaptability. At 2 mM, ASA upregulated antioxidant genes (APX1, POD1, SODC) and photosynthesis genes (RbcS1, PsbS, POR), reducing cold-induced oxidative stress and preserving chloroplast function, thereby enhancing cold tolerance and crop resilience under climate stress.
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spelling doaj-art-29a12d11f06443a8aecef3e20ce1b96a2025-08-20T02:23:51ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2025-06-011610.3389/fpls.2025.15897061589706Exogenous acetylsalicylic acid mitigates cold stress in common bean seedlings by enhancing antioxidant defense and photosynthetic efficiencyBarkat Ali0Sujon Kumar1Xiyu Sui2Jianpo Niu3Junqi Yang4Mengni Zheng5Yi Tang6Huanxiu Li7College of Horticulture, Sichuan Agricultural University, Chengdu, ChinaTriticeae Research Institute, Sichuan Agricultural University, Chengdu, ChinaCollege of Horticulture, Sichuan Agricultural University, Chengdu, ChinaCollege of Horticulture, Sichuan Agricultural University, Chengdu, ChinaCollege of Horticulture, Sichuan Agricultural University, Chengdu, ChinaCollege of Horticulture, Sichuan Agricultural University, Chengdu, ChinaCollege of Horticulture, Sichuan Agricultural University, Chengdu, ChinaCollege of Horticulture, Sichuan Agricultural University, Chengdu, ChinaCold stress severely limits the growth and productivity of common bean (Phaseolus vulgaris L.) seedlings, particularly during early development. Exogenous application of acetylsalicylic acid (ASA) has proven to be an effective strategy for enhancing cold tolerance. This study investigates the usefulness of exogenous ASA in enhancing cold tolerance in common bean seedlings exposed to cold stress of 5°C for 12 and 24 hours, along with a control (0h). ASA treatments (1 mM and 2 mM) significantly improved critical physiological and biochemical parameters, including photosynthesis, chlorophyll and carotenoid concentrations, oxidative stress markers, malondialdehyde, electrical conductivity, total soluble proteins (MDA, EC, SP), and antioxidant enzyme activity. Under cold stress, ASA2 constantly outperformed the other treatments. Following a 12-hour period, ASA2 showed increased chlorophyll concentrations (8.88%) and augmented Chl a levels (21.25%), alongside reducing MDA by 24.96% and SP by 67.1%. After 24 h, ASA2 demonstrated a slight increase in chlorophyll (4.26%) and raised Chl a (25.33%), with a significant reduction in MDA (16.5%) and SP (68.3%). ASA1 showed enhancements, mainly in Chl b (39.89% at 12 h) and antioxidant enzymes, with notable increases in SOD (113.17% at 12 h) and POD (110.98% at 12 h). Correlation studies indicated significant positive relationships between antioxidant enzyme activity such as, superoxide dismutase, catalase, peroxidase, ascorbate peroxidase (SOD, CAT, POD, and APX) and photosynthetic efficiency. Principal component analysis (PCA) identified ASA2 as the most effective treatment for enhancing stress resilience, accounting for the largest variance in membrane integrity and reduction of oxidative stress. Network analysis further confirmed that ASA2 strengthened the connections between photosynthesis and antioxidant activity, with more resilient and interconnected nodes indicating improved stress adaptability. At 2 mM, ASA upregulated antioxidant genes (APX1, POD1, SODC) and photosynthesis genes (RbcS1, PsbS, POR), reducing cold-induced oxidative stress and preserving chloroplast function, thereby enhancing cold tolerance and crop resilience under climate stress.https://www.frontiersin.org/articles/10.3389/fpls.2025.1589706/fullcommon beancold stressacetylsalicylic acidphysiochemical activityantioxidant enzymes
spellingShingle Barkat Ali
Sujon Kumar
Xiyu Sui
Jianpo Niu
Junqi Yang
Mengni Zheng
Yi Tang
Huanxiu Li
Exogenous acetylsalicylic acid mitigates cold stress in common bean seedlings by enhancing antioxidant defense and photosynthetic efficiency
Frontiers in Plant Science
common bean
cold stress
acetylsalicylic acid
physiochemical activity
antioxidant enzymes
title Exogenous acetylsalicylic acid mitigates cold stress in common bean seedlings by enhancing antioxidant defense and photosynthetic efficiency
title_full Exogenous acetylsalicylic acid mitigates cold stress in common bean seedlings by enhancing antioxidant defense and photosynthetic efficiency
title_fullStr Exogenous acetylsalicylic acid mitigates cold stress in common bean seedlings by enhancing antioxidant defense and photosynthetic efficiency
title_full_unstemmed Exogenous acetylsalicylic acid mitigates cold stress in common bean seedlings by enhancing antioxidant defense and photosynthetic efficiency
title_short Exogenous acetylsalicylic acid mitigates cold stress in common bean seedlings by enhancing antioxidant defense and photosynthetic efficiency
title_sort exogenous acetylsalicylic acid mitigates cold stress in common bean seedlings by enhancing antioxidant defense and photosynthetic efficiency
topic common bean
cold stress
acetylsalicylic acid
physiochemical activity
antioxidant enzymes
url https://www.frontiersin.org/articles/10.3389/fpls.2025.1589706/full
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