Study on the regulation of gastric cancer cell apoptosis by LACTB through mitochondrial autophagy pathway

Study on the regulation of gastric cancer cell apoptosis by LACTB through mitochondrial autophagy pathway

Abstract This study aimed to determine whether β-lactamase-like protein (Lactamase-β, LACTB) influences apoptosis in gastric cancer cells by modulating mitochondrial autophagy through the PTEN-induced putative kinase 1 (PINK1) or Parkin pathway. Firstly, the expression level of LACTB in gastric canc...

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Bibliographic Details
Main Authors: Wei Nie, Lihua Hu, Zhiqiang Yan, Qian Wang, Shui He, Xiaoqiang Gao, Fang Yang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Gastric cancer
β-lactamase-like protein
Apoptosis
Mitophagy
PINK1/Parkin pathway
Online Access:https://doi.org/10.1038/s41598-025-06047-0
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