Trifarotene alleviates skin photoaging injury by inhibition of JNK/c-Jun/MMPs

Trifarotene alleviates skin photoaging injury by inhibition of JNK/c-Jun/MMPs

Long-term exposure to ultraviolet (UV) radiation induces skin photoaging, which manifests as oxidative stress, inflammation, and collagen degradation. Multiple approaches (topical or systemic retinoids, antioxidants, alpha-hydroxy acids, laser, surgery) are used in the treatment of photoaged skin, a...

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Bibliographic Details
Main Authors: Fei Xuan, Yang Lele Zixin, Zhang Jingjing, Li Xiang, Pan Mengtian, Xu Guangchen, Zhang Cuixia, Liu Fei, Fang Weirong
Format: Article
Language:English
Published: Sciendo 2024-09-01
Series:Acta Pharmaceutica
Subjects:
trifarotene
skin photoaging
uv
matrix metalloproteinases
inflammatory factors
Online Access:https://doi.org/10.2478/acph-2024-0025
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