Transcriptome and translatome comparison of tissues from Arabidopsis thaliana

Abstract Translation is one of the multiple complementary steps that orchestrates gene activity. In contrast to the straightforwardness of transcriptional surveys, genome-wide profiles of the translational landscape of plant cells remain technically challenging and are thus less well explored. Prote...

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Main Authors: Isabel Cristina Vélez-Bermúdez, Wen-Dar Lin, Shu-Jen Chou, Ai-Ping Chen, Wolfgang Schmidt
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-025-04805-3
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author Isabel Cristina Vélez-Bermúdez
Wen-Dar Lin
Shu-Jen Chou
Ai-Ping Chen
Wolfgang Schmidt
author_facet Isabel Cristina Vélez-Bermúdez
Wen-Dar Lin
Shu-Jen Chou
Ai-Ping Chen
Wolfgang Schmidt
author_sort Isabel Cristina Vélez-Bermúdez
collection DOAJ
description Abstract Translation is one of the multiple complementary steps that orchestrates gene activity. In contrast to the straightforwardness of transcriptional surveys, genome-wide profiles of the translational landscape of plant cells remain technically challenging and are thus less well explored. Protein-coding genes are expressed at a variable degree of efficiency, resulting in pronounced discordance among the regulatory levels that govern gene activity. Ribo-Seq is an extremely useful tool for estimating translation efficiency, but the data sets available for plants are limited. Here, we compare inventories of expressed and translated RNA populations, generated by mRNA sequencing (RNA-Seq) and ribosome footprinting (Ribo-Seq) from shoots and roots of Arabidopsis thaliana seedlings. Our data set provides information on the translational fitness of protein-coding mRNAs that may aid in obtaining a comprehensive picture of the regulatory levels governing genes activity across the genome.
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spelling doaj-art-29932cb3fd6c41fd9806f77fa80939c22025-08-20T02:10:16ZengNature PortfolioScientific Data2052-44632025-03-0112111010.1038/s41597-025-04805-3Transcriptome and translatome comparison of tissues from Arabidopsis thalianaIsabel Cristina Vélez-Bermúdez0Wen-Dar Lin1Shu-Jen Chou2Ai-Ping Chen3Wolfgang Schmidt4Institute of Plant and Microbial Biology, Academia SinicaInstitute of Plant and Microbial Biology, Bioinformatics Core Lab, Academia SinicaInstitute of Plant and Microbial Biology, Genomic Technology Core, Academia SinicaInstitute of Plant and Microbial Biology, Genomic Technology Core, Academia SinicaInstitute of Plant and Microbial Biology, Academia SinicaAbstract Translation is one of the multiple complementary steps that orchestrates gene activity. In contrast to the straightforwardness of transcriptional surveys, genome-wide profiles of the translational landscape of plant cells remain technically challenging and are thus less well explored. Protein-coding genes are expressed at a variable degree of efficiency, resulting in pronounced discordance among the regulatory levels that govern gene activity. Ribo-Seq is an extremely useful tool for estimating translation efficiency, but the data sets available for plants are limited. Here, we compare inventories of expressed and translated RNA populations, generated by mRNA sequencing (RNA-Seq) and ribosome footprinting (Ribo-Seq) from shoots and roots of Arabidopsis thaliana seedlings. Our data set provides information on the translational fitness of protein-coding mRNAs that may aid in obtaining a comprehensive picture of the regulatory levels governing genes activity across the genome.https://doi.org/10.1038/s41597-025-04805-3
spellingShingle Isabel Cristina Vélez-Bermúdez
Wen-Dar Lin
Shu-Jen Chou
Ai-Ping Chen
Wolfgang Schmidt
Transcriptome and translatome comparison of tissues from Arabidopsis thaliana
Scientific Data
title Transcriptome and translatome comparison of tissues from Arabidopsis thaliana
title_full Transcriptome and translatome comparison of tissues from Arabidopsis thaliana
title_fullStr Transcriptome and translatome comparison of tissues from Arabidopsis thaliana
title_full_unstemmed Transcriptome and translatome comparison of tissues from Arabidopsis thaliana
title_short Transcriptome and translatome comparison of tissues from Arabidopsis thaliana
title_sort transcriptome and translatome comparison of tissues from arabidopsis thaliana
url https://doi.org/10.1038/s41597-025-04805-3
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