Мodern methods of diagnosis of endometrial carcinoma
The main methods of histological diagnosis of endometrial carcinoma are dilatation and curettage, fractional curettage, and diagnostic hysteroscopy with endometrial biopsy. This retrospective study aims to compare the preoperative histological results obtained by different diagnostic methods with th...
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| Format: | Article |
| Language: | English |
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Medical University - Pleven
2024-11-01
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| Series: | Journal of Biomedical & Clinical Research |
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| Online Access: | https://jbcr.arphahub.com/article/138140/download/pdf/ |
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| author | Dimitar Dimitrov Nadezhda Hinkova Teodora Semova Zornitsa Gorcheva Mirela Vasileva Elitsa Petkova |
| author_facet | Dimitar Dimitrov Nadezhda Hinkova Teodora Semova Zornitsa Gorcheva Mirela Vasileva Elitsa Petkova |
| author_sort | Dimitar Dimitrov |
| collection | DOAJ |
| description | The main methods of histological diagnosis of endometrial carcinoma are dilatation and curettage, fractional curettage, and diagnostic hysteroscopy with endometrial biopsy. This retrospective study aims to compare the preoperative histological results obtained by different diagnostic methods with the postoperative ones in patients with endometrial carcinoma and determine the most accurate and safest method for diagnosing the disease. From 06.2020 to 09.2023, a retrospective study was conducted on 80 patients with histologically proven carcinoma of the endometrium, treated at University Hospital Saint Marina-Pleven. The mean age of the patients was 58.04 ± 10.46, ranging from 28 to 78. The comparative analysis of the discrepancies of the histological verification methods in the evaluation of the preoperative and postoperative histological result showed that a statistically significantly higher percentage of discrepancies (19.5%) had the dilatation and curettage compared to the zero discrepancy of the hysteroscopy (0.0%). The relative proportion of discrepancies of the fractional curettage is 14.3%. The cytological result was negative for tumor cells in 97.5% and positive in 2.5%. In all patients with a positive cytological result for tumor cells, the method of histological verification was dilatation and curettage. Performing diagnostic hysteroscopy and observing safety principles such as creating low intrauterine pressure and short operative time is a safe and reliable method for diagnosing endometrial carcinoma. |
| format | Article |
| id | doaj-art-298e53470d4c44c38180bb64ce7e310c |
| institution | OA Journals |
| issn | 1313-9053 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Medical University - Pleven |
| record_format | Article |
| series | Journal of Biomedical & Clinical Research |
| spelling | doaj-art-298e53470d4c44c38180bb64ce7e310c2025-08-20T01:54:18ZengMedical University - PlevenJournal of Biomedical & Clinical Research1313-90532024-11-0117219720410.3897/jbcr.e138140138140Мodern methods of diagnosis of endometrial carcinomaDimitar Dimitrov0Nadezhda Hinkova1Teodora Semova2Zornitsa Gorcheva3Mirela Vasileva4Elitsa Petkova5University Hospital Saint MarinaUniversity Hospital Saint MarinaMedical UniversityMedical UniversityUniversity Hospital Saint MarinaMedical UniversityThe main methods of histological diagnosis of endometrial carcinoma are dilatation and curettage, fractional curettage, and diagnostic hysteroscopy with endometrial biopsy. This retrospective study aims to compare the preoperative histological results obtained by different diagnostic methods with the postoperative ones in patients with endometrial carcinoma and determine the most accurate and safest method for diagnosing the disease. From 06.2020 to 09.2023, a retrospective study was conducted on 80 patients with histologically proven carcinoma of the endometrium, treated at University Hospital Saint Marina-Pleven. The mean age of the patients was 58.04 ± 10.46, ranging from 28 to 78. The comparative analysis of the discrepancies of the histological verification methods in the evaluation of the preoperative and postoperative histological result showed that a statistically significantly higher percentage of discrepancies (19.5%) had the dilatation and curettage compared to the zero discrepancy of the hysteroscopy (0.0%). The relative proportion of discrepancies of the fractional curettage is 14.3%. The cytological result was negative for tumor cells in 97.5% and positive in 2.5%. In all patients with a positive cytological result for tumor cells, the method of histological verification was dilatation and curettage. Performing diagnostic hysteroscopy and observing safety principles such as creating low intrauterine pressure and short operative time is a safe and reliable method for diagnosing endometrial carcinoma.https://jbcr.arphahub.com/article/138140/download/pdf/Endometrial cancerdilatation and curettagehyst |
| spellingShingle | Dimitar Dimitrov Nadezhda Hinkova Teodora Semova Zornitsa Gorcheva Mirela Vasileva Elitsa Petkova Мodern methods of diagnosis of endometrial carcinoma Journal of Biomedical & Clinical Research Endometrial cancer dilatation and curettage hyst |
| title | Мodern methods of diagnosis of endometrial carcinoma |
| title_full | Мodern methods of diagnosis of endometrial carcinoma |
| title_fullStr | Мodern methods of diagnosis of endometrial carcinoma |
| title_full_unstemmed | Мodern methods of diagnosis of endometrial carcinoma |
| title_short | Мodern methods of diagnosis of endometrial carcinoma |
| title_sort | amp 1052 odern methods of diagnosis of endometrial carcinoma |
| topic | Endometrial cancer dilatation and curettage hyst |
| url | https://jbcr.arphahub.com/article/138140/download/pdf/ |
| work_keys_str_mv | AT dimitardimitrov amp1052odernmethodsofdiagnosisofendometrialcarcinoma AT nadezhdahinkova amp1052odernmethodsofdiagnosisofendometrialcarcinoma AT teodorasemova amp1052odernmethodsofdiagnosisofendometrialcarcinoma AT zornitsagorcheva amp1052odernmethodsofdiagnosisofendometrialcarcinoma AT mirelavasileva amp1052odernmethodsofdiagnosisofendometrialcarcinoma AT elitsapetkova amp1052odernmethodsofdiagnosisofendometrialcarcinoma |