B cells are not drivers of stromal cell activation during acute CNS infection

B cells are not drivers of stromal cell activation during acute CNS infection

Abstract Background CNS stromal cells, especially fibroblasts and endothelial cells, support leukocyte accumulation through upregulation of adhesion molecules and lymphoid chemokines. While chronically activated fibroblast networks can drive pathogenic immune cell aggregates known as tertiary lympho...

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Bibliographic Details
Main Authors: Brendan T. Boylan, Mihyun Hwang, Elyse Brozost, Hyunsuk Oh, Alexei V. Tumanov, Antoine Louveau, Cornelia C. Bergmann
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Neuroinflammation
Online Access:https://doi.org/10.1186/s12974-025-03491-7
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