Cytogenetic landscape aberrations in paediatric acute lymphoblastic leukaemia — a polish paediatric population treated according to ALL-IC BFM 2009 protocol

Cytogenetic landscape aberrations in paediatric acute lymphoblastic leukaemia — a polish paediatric population treated according to ALL-IC BFM 2009 protocol

Abstract Genetic findings are important independent prognostic factors in childhood acute lymphoblastic leukaemia (ALL). This study presents cytogenetic data correlated with clinical factors of 1337 patients aged 1–18 years with newly diagnosed ALL treated between 2011 and 2018 under the Polish ALL...

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Main Authors: Monika Lejman, Borys Styka, Joanna Zawitkowska, Anna Pastwińska, Ewa Studniak, Katarzyna Skonieczka, Marta Zacharczuk, Katarzyna Całka, Olga Haus, Panasiuk Barbara, Beata Sadowska, Anna Przybyłowicz-Chalecka, Małgorzata Jarmuż-Szymczak, Maria Malm, Bartłomiej Drop, Jerzy R. Kowalczyk
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Cytogenetics aberrations
BCR:ABL1
KMT2A-r
ETV6:RUNX1
Karyotype
Childhood acute lymphoblastic leukaemia
Online Access:https://doi.org/10.1038/s41598-025-12762-5
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