<i>Swertiamarin</i> Rescues 3-NPA-Induced Defective Follicular Development via Modulating the NRF2/HO-1 Signaling Pathway in Granulosa Cells

<i>Swertiamarin</i> Rescues 3-NPA-Induced Defective Follicular Development via Modulating the NRF2/HO-1 Signaling Pathway in Granulosa Cells

The normal development of ovarian follicles, characterized by oocyte growth and granulosa cell proliferation, is essential for maintaining female fertility. Elevated oxidative stress, resulting from various in vivo and in vitro factors, significantly impairs follicular development, ovulation, and ov...

Full description

Saved in:
Bibliographic Details
Main Authors: Luoyu Mo, Gan Yang, Dongju Liu, Huai Zhang, Xiaodong Dong, Fuyong Li, Ziqian Huang, Dini Zhang, Yan Xiong, Xianrong Xiong, Honghong He, Jian Li, Shi Yin
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Antioxidants
Subjects:
<i>Swertiamarin</i>
oxidative stress
follicle development
granulosa cell
NRF2/HO-1 pathway
Online Access:https://www.mdpi.com/2076-3921/14/7/794
Tags: Add Tag
No Tags, Be the first to tag this record!
Be the first to leave a comment!
You must be logged in first

Similar Items