Effect of quercetin on the transport of ritonavir to the central nervous system in vitro and in vivo
The aim of this study was to identify an effective flavonoid that could improve the intracellular accumulation of ritonavir in human brain-microvascular endothelial cells (HBMECs). An in vivo experiment on Sprague-Dawley rats was then designed to further determine the flavonoid’s impact on the pharm...
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Main Authors: | Liang Gongwen, Li Na, Ma Liping, Qian Zhonglian, Sun Yuwen, Shi Luwen, Zhao Libo |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2016-03-01
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Series: | Acta Pharmaceutica |
Subjects: | |
Online Access: | https://doi.org/10.1515/acph-2016-0009 |
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