FOLLOW-UP OF METHOTREXATE EFFECTIVENESS IN A PATIENT WITH JUVENILE POLYARTHRITIS
The article presents a short review of the current notion of the leading role methotrexate in treatment of most clinical variants ofjuvenile idiopathic arthritis. The authors demonstrate that methotrexate is a “gold standard” of antirheumatic therapy and the key disease-modifying drug of pediatric r...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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Union of pediatricians of Russia
2014-07-01
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| Series: | Педиатрическая фармакология |
| Subjects: | |
| Online Access: | https://www.pedpharma.ru/jour/article/view/81 |
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| author | L. A. Balykova O. M. Soldatov N. V. Shchekina A. V. Krasnopol'skaya A. N. Os'kina |
| author_facet | L. A. Balykova O. M. Soldatov N. V. Shchekina A. V. Krasnopol'skaya A. N. Os'kina |
| author_sort | L. A. Balykova |
| collection | DOAJ |
| description | The article presents a short review of the current notion of the leading role methotrexate in treatment of most clinical variants ofjuvenile idiopathic arthritis. The authors demonstrate that methotrexate is a “gold standard” of antirheumatic therapy and the key disease-modifying drug of pediatric rheumatology. The emphasis is laid on safety profile and advantages of parenteral administration thereof. The article presents follow-up of a clinical case involving use of dosage form of methotrexate in the dose of 15 mg/m per week for subcutaneous administration in a patient with polyarticular juvenile idiopathic arthritis featuring insufficient effectiveness and low tolerance of the oral drug. Prescription of methotrexate for subcutaneous administration helped to terminate progression of the disease and pain syndrome and improve function of the affected joints and the patient’s quality of life. |
| format | Article |
| id | doaj-art-296d949243d948f596e4eeae8ee1bc1c |
| institution | DOAJ |
| issn | 1727-5776 2500-3089 |
| language | Russian |
| publishDate | 2014-07-01 |
| publisher | Union of pediatricians of Russia |
| record_format | Article |
| series | Педиатрическая фармакология |
| spelling | doaj-art-296d949243d948f596e4eeae8ee1bc1c2025-08-20T02:54:33ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892014-07-0111410310810.15690/pf.v11i4.107381FOLLOW-UP OF METHOTREXATE EFFECTIVENESS IN A PATIENT WITH JUVENILE POLYARTHRITISL. A. Balykova0O. M. Soldatov1N. V. Shchekina2A. V. Krasnopol'skaya3A. N. Os'kina4Ogaryov Mordovian State University, Saransk, Russian FederationRepublican Pediatric Clinical Hospital No. 2, Saransk, Republic of Mordovia, Russian FederationRepublican Pediatric Clinical Hospital No. 2, Saransk, Republic of Mordovia, Russian FederationOgaryov Mordovian State University, Saransk, Russian FederationOgaryov Mordovian State University, Saransk, Russian FederationThe article presents a short review of the current notion of the leading role methotrexate in treatment of most clinical variants ofjuvenile idiopathic arthritis. The authors demonstrate that methotrexate is a “gold standard” of antirheumatic therapy and the key disease-modifying drug of pediatric rheumatology. The emphasis is laid on safety profile and advantages of parenteral administration thereof. The article presents follow-up of a clinical case involving use of dosage form of methotrexate in the dose of 15 mg/m per week for subcutaneous administration in a patient with polyarticular juvenile idiopathic arthritis featuring insufficient effectiveness and low tolerance of the oral drug. Prescription of methotrexate for subcutaneous administration helped to terminate progression of the disease and pain syndrome and improve function of the affected joints and the patient’s quality of life.https://www.pedpharma.ru/jour/article/view/81juvenile idiopathic arthritispolyarthritismethotrexate |
| spellingShingle | L. A. Balykova O. M. Soldatov N. V. Shchekina A. V. Krasnopol'skaya A. N. Os'kina FOLLOW-UP OF METHOTREXATE EFFECTIVENESS IN A PATIENT WITH JUVENILE POLYARTHRITIS Педиатрическая фармакология juvenile idiopathic arthritis polyarthritis methotrexate |
| title | FOLLOW-UP OF METHOTREXATE EFFECTIVENESS IN A PATIENT WITH JUVENILE POLYARTHRITIS |
| title_full | FOLLOW-UP OF METHOTREXATE EFFECTIVENESS IN A PATIENT WITH JUVENILE POLYARTHRITIS |
| title_fullStr | FOLLOW-UP OF METHOTREXATE EFFECTIVENESS IN A PATIENT WITH JUVENILE POLYARTHRITIS |
| title_full_unstemmed | FOLLOW-UP OF METHOTREXATE EFFECTIVENESS IN A PATIENT WITH JUVENILE POLYARTHRITIS |
| title_short | FOLLOW-UP OF METHOTREXATE EFFECTIVENESS IN A PATIENT WITH JUVENILE POLYARTHRITIS |
| title_sort | follow up of methotrexate effectiveness in a patient with juvenile polyarthritis |
| topic | juvenile idiopathic arthritis polyarthritis methotrexate |
| url | https://www.pedpharma.ru/jour/article/view/81 |
| work_keys_str_mv | AT labalykova followupofmethotrexateeffectivenessinapatientwithjuvenilepolyarthritis AT omsoldatov followupofmethotrexateeffectivenessinapatientwithjuvenilepolyarthritis AT nvshchekina followupofmethotrexateeffectivenessinapatientwithjuvenilepolyarthritis AT avkrasnopolskaya followupofmethotrexateeffectivenessinapatientwithjuvenilepolyarthritis AT anoskina followupofmethotrexateeffectivenessinapatientwithjuvenilepolyarthritis |