Is Altered Surfactant Protein Gene Expression in Peripheral Blood Associated with COVID-19 Disease Severity?

Is Altered Surfactant Protein Gene Expression in Peripheral Blood Associated with COVID-19 Disease Severity?

<b>Background/Objectives:</b> Severe COVID-19 pneumonia damages alveolar type II cells and disrupts surfactant homeostasis, contributing to acute respiratory distress syndrome (ARDS). Surfactant proteins (SP-A, SP-B, SP-C, SP-D) are critical for reducing alveolar surface tension and for...

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Bibliographic Details
Main Authors: Suna Koc, Kamil Cankut Senturk, Sefa Cetinkaya, Guven Yenmis, Hulya Arkan, Mahmut Demirbilek, Pinar Acar, Erhan Arikan, Mehmet Dokur
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Diagnostics
Subjects:
COVID-19
surfactant protein
disease severity
gene expression
SFTPD
Online Access:https://www.mdpi.com/2075-4418/15/13/1690
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