Kinetics of hematological and biochemical biomarkers are key tools for monitoring disease progression in Marburg virus-infected patients in Rwanda

Kinetics of hematological and biochemical biomarkers are key tools for monitoring disease progression in Marburg virus-infected patients in Rwanda

Abstract Marburg Virus Disease (MVD) is a severe disease with a fatality rate of up to 90%. Limited studies have suggested hematological and biochemical biomarkers for managing MVD, but data on key markers correlated with MVD development are scarce. This study aimed to investigate the biosignatures...

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Main Authors: Jean Claude Mugisha, Etienne Kayigi, Noel Gahamanyi, Henri Desire Uwayo, Fidele Umwanankabandi, Pierre Gashema, Edison Rwagasore, David Turatsinze, Menelas Nkeshimana, Misbah Gashegu, Edward Ntagwabira, Lyndah Makayoto, Jean Claude Semuto Ngabonziza, Isabelle Mukagatare, Albert Tuyishime, Nadine Rujeni, Leon Mutesa, Eric Seruyange, Sanctus Musafiri, Theogene Twagirumugabe, Jean de Dieu Harelimana, Claude Mambo Muvunyi
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Marburg virus
Kinetics
Biomarkers
Disease progression
Rwanda
Online Access:https://doi.org/10.1038/s41598-025-04732-8
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