Unveiling the metabolic roles: how lead exposure elevates uric acid levels

Unveiling the metabolic roles: how lead exposure elevates uric acid levels

Abstract Chronic lead (Pb) exposure remains a global public health concern throughout the world. Particularly the populations in industrial or polluted environments tend to have an increased risk of metabolic imbalance in uric acid (UA). However, the metabolic profile alteration under Pb exposure-in...

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Main Authors: Wanlu Liu, Yaotang Deng, Guoliang Li, Zhiqiang Zhao, Xinyu Zhu, Jiazhen Zhou, Mushi Yi, Simin Xian, Yue Hu, Youyi Wu, Qiaoyuan Yang, Lili Liu, Yansen Bai
Format: Article
Language:English
Published: SpringerOpen 2025-08-01
Series:Environmental Sciences Europe
Subjects:
Lead exposure
Metabolomics
Uric acid
Estimated glomerular filtration rate
Serial mediating effects
Online Access:https://doi.org/10.1186/s12302-025-01186-7
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