Thrombotic Microangiopathy Secondary to Sirolimus Monotherapy in Orthotopic Liver Transplant

Sirolimus is a mammalian target of rapamycin (mTOR) inhibitor often used in clinical conjunction with calcineurin inhibitors (CNIs) or mycophenolate mofetil to prevent solid organ transplant rejection. While nephrotoxicity is a well-known side effect of CNIs, renal injury because of mTOR inhibitors...

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Bibliographic Details
Main Authors: Tabeer Rana, Shivani Shah, Lydia Du, Sheena Mago, Tavankit Singh, Mark Bunker
Format: Article
Language:English
Published: American College of Physicians 2024-06-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2023.0960
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