Thrombotic Microangiopathy Secondary to Sirolimus Monotherapy in Orthotopic Liver Transplant
Sirolimus is a mammalian target of rapamycin (mTOR) inhibitor often used in clinical conjunction with calcineurin inhibitors (CNIs) or mycophenolate mofetil to prevent solid organ transplant rejection. While nephrotoxicity is a well-known side effect of CNIs, renal injury because of mTOR inhibitors...
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| Main Authors: | Tabeer Rana, Shivani Shah, Lydia Du, Sheena Mago, Tavankit Singh, Mark Bunker |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
American College of Physicians
2024-06-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2023.0960 |
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