Psychological factors and obesity, not thyroid biomarkers, predict thyroid-dependent quality of life in treated hypothyroidism: a cross-sectional study

Psychological factors and obesity, not thyroid biomarkers, predict thyroid-dependent quality of life in treated hypothyroidism: a cross-sectional study

Abstract Background A significant number of patients with primary hypothyroidism report persistent symptoms and decreased quality of life (QoL) despite biochemically adequate levothyroxine replacement. Individual variations in thyroxine conversion, autoimmune inflammation, and psychological factors...

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Main Authors: Bence Bakos, Tibor Solymosi, Balázs Szili, Ágnes Vincze, Szilvia Mészáros, Márk Stempler, Richárd Ármós, András Kiss, Anna Bakos, Nikolette Szücs, Péter Reismann, Judit Tőke, Péter Pusztai, Péter Lakatos, István Takács
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Endocrine Disorders
Subjects:
Hypothyroidism
Quality of life
Somatosensory amplification
Depression
Obesity
Reverse-T3
Online Access:https://doi.org/10.1186/s12902-025-01962-9
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