Wolbachia elevates host methyltransferase expression and alters the m6A methylation landscape in Aedes aegypti mosquito cells

Wolbachia elevates host methyltransferase expression and alters the m6A methylation landscape in Aedes aegypti mosquito cells

Abstract Wolbachia pipientis is an intracellular endosymbiotic bacterium that blocks the replication of several arboviruses in transinfected Aedes aegypti mosquitoes, yet its antiviral mechanism remains unknown. For the first time, we employed Nanopore direct RNA sequencing technology to investigate...

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Bibliographic Details
Main Authors: Michael Leitner, Valentine Murigneux, Kayvan Etebari, Sassan Asgari
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Microbiology
Subjects:
Aedes aegypti
wAlbB
Wolbachia
m6A
Post-transcriptional modification
TMEM41B
Online Access:https://doi.org/10.1186/s12866-025-03898-5
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