A Rare Case of Desmoid Fibromatosis in a Pediatric Patient: Surgical Management and Outcomes

Desmoid fibromatosis (DF) is a rare, locally aggressive tumor arising from the abdominal fascia or musculoaponeurosis, commonly affecting individuals between 15 and 60 years of age. We present a case of a 13-year-old boy with a 9-month history of progressive swelling in the left posterior thigh. Mag...

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Main Authors: Boon Tat Yeap, MD, MMed, Ikhwan Nasir, MD, MMed, Thai Hau Koo, MD, Aaron Gerarde Paul, MD, MMed, Mohd Hazeman Zakaria, MD, MMed
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Radiology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S1930043325000834
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author Boon Tat Yeap, MD, MMed
Ikhwan Nasir, MD, MMed
Thai Hau Koo, MD
Aaron Gerarde Paul, MD, MMed
Mohd Hazeman Zakaria, MD, MMed
author_facet Boon Tat Yeap, MD, MMed
Ikhwan Nasir, MD, MMed
Thai Hau Koo, MD
Aaron Gerarde Paul, MD, MMed
Mohd Hazeman Zakaria, MD, MMed
author_sort Boon Tat Yeap, MD, MMed
collection DOAJ
description Desmoid fibromatosis (DF) is a rare, locally aggressive tumor arising from the abdominal fascia or musculoaponeurosis, commonly affecting individuals between 15 and 60 years of age. We present a case of a 13-year-old boy with a 9-month history of progressive swelling in the left posterior thigh. Magnetic resonance imaging (MRI) revealed a soft tissue tumor encasing the sciatic nerve. A biopsy confirmed the diagnosis of DF, showing spindle cells arranged in fascicles. The patient underwent wide local excision of the tumor with preservation of the sciatic nerve. Postoperative recovery was smooth, and 1-year follow-up MRI showed no recurrence. Surgical excision remains the primary treatment, especially in symptomatic patients, although recurrence is common even with negative margins. This case underscores the importance of regular follow-up for DF and a multidisciplinary approach to optimize management and surveillance.
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spelling doaj-art-294c8cd1f961426a92172dbd3c4865702025-08-20T03:06:00ZengElsevierRadiology Case Reports1930-04332025-05-012052384238710.1016/j.radcr.2025.01.083A Rare Case of Desmoid Fibromatosis in a Pediatric Patient: Surgical Management and OutcomesBoon Tat Yeap, MD, MMed0Ikhwan Nasir, MD, MMed1Thai Hau Koo, MD2Aaron Gerarde Paul, MD, MMed3Mohd Hazeman Zakaria, MD, MMed4Department of Anaesthesiology and Intensive Care, Hospital Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia; Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, MalaysiaDepartment of Anaesthesiology and Intensive Care, Hospital Universiti Malaysia Sabah, Kota Kinabalu, Sabah, MalaysiaDepartment of Internal Medicine, School of Medical Sciences, Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, MalaysiaDepartment of Orthopaedics, Hospital Queen Elizabeth, Kota Kinabalu, Sabah, MalaysiaDepartment of Radiology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor, Malaysia; Corresponding author.Desmoid fibromatosis (DF) is a rare, locally aggressive tumor arising from the abdominal fascia or musculoaponeurosis, commonly affecting individuals between 15 and 60 years of age. We present a case of a 13-year-old boy with a 9-month history of progressive swelling in the left posterior thigh. Magnetic resonance imaging (MRI) revealed a soft tissue tumor encasing the sciatic nerve. A biopsy confirmed the diagnosis of DF, showing spindle cells arranged in fascicles. The patient underwent wide local excision of the tumor with preservation of the sciatic nerve. Postoperative recovery was smooth, and 1-year follow-up MRI showed no recurrence. Surgical excision remains the primary treatment, especially in symptomatic patients, although recurrence is common even with negative margins. This case underscores the importance of regular follow-up for DF and a multidisciplinary approach to optimize management and surveillance.http://www.sciencedirect.com/science/article/pii/S1930043325000834Desmoid fibromatosisPaediatricsRadiologyOrthopedicsOncology
spellingShingle Boon Tat Yeap, MD, MMed
Ikhwan Nasir, MD, MMed
Thai Hau Koo, MD
Aaron Gerarde Paul, MD, MMed
Mohd Hazeman Zakaria, MD, MMed
A Rare Case of Desmoid Fibromatosis in a Pediatric Patient: Surgical Management and Outcomes
Radiology Case Reports
Desmoid fibromatosis
Paediatrics
Radiology
Orthopedics
Oncology
title A Rare Case of Desmoid Fibromatosis in a Pediatric Patient: Surgical Management and Outcomes
title_full A Rare Case of Desmoid Fibromatosis in a Pediatric Patient: Surgical Management and Outcomes
title_fullStr A Rare Case of Desmoid Fibromatosis in a Pediatric Patient: Surgical Management and Outcomes
title_full_unstemmed A Rare Case of Desmoid Fibromatosis in a Pediatric Patient: Surgical Management and Outcomes
title_short A Rare Case of Desmoid Fibromatosis in a Pediatric Patient: Surgical Management and Outcomes
title_sort rare case of desmoid fibromatosis in a pediatric patient surgical management and outcomes
topic Desmoid fibromatosis
Paediatrics
Radiology
Orthopedics
Oncology
url http://www.sciencedirect.com/science/article/pii/S1930043325000834
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