Sedative exposure and mortality in intracranial hypertensive tuberculous meningitis: a cohort study with propensity-score matching and machine learning analysis

Sedative exposure and mortality in intracranial hypertensive tuberculous meningitis: a cohort study with propensity-score matching and machine learning analysis

BackgroundTuberculous meningitis (TBM) complicated by intracranial hypertension requires aggressive neurocritical care, yet the mortality impact of sedative and antipsychotic exposure remains controversial. This study investigates the association between sedative exposure and mortality while identif...

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Bibliographic Details
Main Authors: Shijuan Cui, Fazheng Shen, Jianing Liang, Fan Li, Xiangyang Wang, Xin Liu, Haigang Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
intracranial hypertension
machine learning
mortality
sedative exposure
tuberculous meningitis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1620858/full
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