Effects of reduced extracellular sodium on proliferation and invasive activity of renal cell carcinoma cell lines

Abstract Hyponatremia is the most common electrolyte disorder in cancer patients and is associated with a worse outcome. This finding has also been reported in patients with metastatic renal cell carcinoma (mRCC). We have previously demonstrated that low extracellular sodium concentrations ([Na+]) i...

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Bibliographic Details
Main Authors: Laura Naldi, Martina Catalano, Maria Elena Melica, Simone Polvani, Dimitri Papini, Ida Landini, Alessandro Peri, Giandomenico Roviello
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-92674-6
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