Inactivation effect and mechanism of ultrasound combined with ultraviolet treatment on Bacillus cereus spores

Bacillus cereus is a common foodborne pathogen, and its formation of strongly resistant spores renders the pathogen difficult to eliminate completely using traditional sterilization methods. This study aimed to investigate the inactivation effect of ultrasound combined with ultraviolet treatment on...

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Main Authors: Yajin Qi, Xiao Hu, Yi Chen, Ruiling Lv, Tian Ding
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Agriculture and Food Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666154324004198
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author Yajin Qi
Xiao Hu
Yi Chen
Ruiling Lv
Tian Ding
author_facet Yajin Qi
Xiao Hu
Yi Chen
Ruiling Lv
Tian Ding
author_sort Yajin Qi
collection DOAJ
description Bacillus cereus is a common foodborne pathogen, and its formation of strongly resistant spores renders the pathogen difficult to eliminate completely using traditional sterilization methods. This study aimed to investigate the inactivation effect of ultrasound combined with ultraviolet treatment on Bacillus cereus spores and the underlying mechanism. The inactivation effect, surface properties, structural changes, heat resistance and germination characteristics, as well as Raman spectroscopy results, were examined. It was found that 20 min of ultrasound combined with ultraviolet treatment resulted in the inactivation of 4.61 log CFU/mL. Structurally, the exosporium and coat were damaged. Moreover, the permeability of the inner membrane increased. Damage to the spores’ structure reduced the heat resistance. Raman spectroscopy indicated that the DNA and proteins were severely damaged.In conclusion, ultrasound combined with ultraviolet treatment demonstrated a synergistic inactivation effect on Bacillus cereus spores by destroying the external structures of the spores, as well as the internal DNA and other substances. This study has preliminarily elucidated the mechanism of ultrasound combined with ultraviolet treatment regarding the inactivation of Bacillus cereus spores, providing a theoretical foundation for its application in food sterilization.
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series Journal of Agriculture and Food Research
spelling doaj-art-292a61de7b2c40d2ac6dec3d09cce3502025-08-20T01:56:42ZengElsevierJournal of Agriculture and Food Research2666-15432024-12-011810138210.1016/j.jafr.2024.101382Inactivation effect and mechanism of ultrasound combined with ultraviolet treatment on Bacillus cereus sporesYajin Qi0Xiao Hu1Yi Chen2Ruiling Lv3Tian Ding4Ningbo Innovation Center, Zhejiang University, Ningbo, 315100, China; College of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang University, Hangzhou, 310058, ChinaCollege of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang University, Hangzhou, 310058, ChinaNingbo Innovation Center, Zhejiang University, Ningbo, 315100, China; College of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang University, Hangzhou, 310058, ChinaNingbo Innovation Center, Zhejiang University, Ningbo, 315100, China; College of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang University, Hangzhou, 310058, China; Corresponding author. Ningbo Innovation Center, Zhejiang University, Ningbo, 315100, China.College of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang University, Hangzhou, 310058, China; Corresponding author.Bacillus cereus is a common foodborne pathogen, and its formation of strongly resistant spores renders the pathogen difficult to eliminate completely using traditional sterilization methods. This study aimed to investigate the inactivation effect of ultrasound combined with ultraviolet treatment on Bacillus cereus spores and the underlying mechanism. The inactivation effect, surface properties, structural changes, heat resistance and germination characteristics, as well as Raman spectroscopy results, were examined. It was found that 20 min of ultrasound combined with ultraviolet treatment resulted in the inactivation of 4.61 log CFU/mL. Structurally, the exosporium and coat were damaged. Moreover, the permeability of the inner membrane increased. Damage to the spores’ structure reduced the heat resistance. Raman spectroscopy indicated that the DNA and proteins were severely damaged.In conclusion, ultrasound combined with ultraviolet treatment demonstrated a synergistic inactivation effect on Bacillus cereus spores by destroying the external structures of the spores, as well as the internal DNA and other substances. This study has preliminarily elucidated the mechanism of ultrasound combined with ultraviolet treatment regarding the inactivation of Bacillus cereus spores, providing a theoretical foundation for its application in food sterilization.http://www.sciencedirect.com/science/article/pii/S2666154324004198Bacillus cereus sporeUltrasoundUltravioletInactivation mechanismHurdle technology
spellingShingle Yajin Qi
Xiao Hu
Yi Chen
Ruiling Lv
Tian Ding
Inactivation effect and mechanism of ultrasound combined with ultraviolet treatment on Bacillus cereus spores
Journal of Agriculture and Food Research
Bacillus cereus spore
Ultrasound
Ultraviolet
Inactivation mechanism
Hurdle technology
title Inactivation effect and mechanism of ultrasound combined with ultraviolet treatment on Bacillus cereus spores
title_full Inactivation effect and mechanism of ultrasound combined with ultraviolet treatment on Bacillus cereus spores
title_fullStr Inactivation effect and mechanism of ultrasound combined with ultraviolet treatment on Bacillus cereus spores
title_full_unstemmed Inactivation effect and mechanism of ultrasound combined with ultraviolet treatment on Bacillus cereus spores
title_short Inactivation effect and mechanism of ultrasound combined with ultraviolet treatment on Bacillus cereus spores
title_sort inactivation effect and mechanism of ultrasound combined with ultraviolet treatment on bacillus cereus spores
topic Bacillus cereus spore
Ultrasound
Ultraviolet
Inactivation mechanism
Hurdle technology
url http://www.sciencedirect.com/science/article/pii/S2666154324004198
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AT ruilinglv inactivationeffectandmechanismofultrasoundcombinedwithultraviolettreatmentonbacilluscereusspores
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