Survey of innate immune responses to Burkholderia pseudomallei in human blood identifies a central role for lipopolysaccharide.

Survey of innate immune responses to Burkholderia pseudomallei in human blood identifies a central role for lipopolysaccharide.

B. pseudomallei is a gram-negative bacterium that causes the tropical infection melioidosis. In northeast Thailand, mortality from melioidosis approaches 40%. As exemplified by the lipopolysaccharide-Toll-like receptor 4 interaction, innate immune responses to invading bacteria are precipitated by a...

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Bibliographic Details
Main Authors: Narisara Chantratita, Sarunporn Tandhavanant, Nicolle D Myers, Sudeshna Seal, Arkhom Arayawichanont, Aroonsri Kliangsa-Ad, Lauren E Hittle, Robert K Ernst, Mary J Emond, Mark M Wurfel, Nicholas P J Day, Sharon J Peacock, T Eoin West
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0081617&type=printable
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