Grading of Aortic Stenosis: Is it More Complicated in Women?

Aortic stenosis (AS) is the most common valvular heart disease and the main indication for valvular replacement in older women. Correct AS grading is mandatory for an adequate selection of patients for both surgical and transcatheter aortic valve replacement. Women and men have different AS severity...

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Main Authors: Dana Cramariuc, Edda Bahlmann, Eva Gerdts
Format: Article
Language:English
Published: Radcliffe Medical Media 2022-11-01
Series:European Cardiology Review
Online Access:https://www.ecrjournal.com/articleindex/ecr.2022.13
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author Dana Cramariuc
Edda Bahlmann
Eva Gerdts
author_facet Dana Cramariuc
Edda Bahlmann
Eva Gerdts
author_sort Dana Cramariuc
collection DOAJ
description Aortic stenosis (AS) is the most common valvular heart disease and the main indication for valvular replacement in older women. Correct AS grading is mandatory for an adequate selection of patients for both surgical and transcatheter aortic valve replacement. Women and men have different AS severity grades at the same level of aortic valve calcification. Moreover, besides having smaller cardiac volumes, left ventricular outflow tract and aortic size, women have a specific pattern of left ventricular structural and functional remodelling in response to the AS-related chronic pressure overload. Here, the sex-specific cardiac changes in AS that make AS grading more challenging in women, with consequences for the management and outcome of this group of patients, are reviewed.
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institution Kabale University
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1758-3764
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publishDate 2022-11-01
publisher Radcliffe Medical Media
record_format Article
series European Cardiology Review
spelling doaj-art-2920b8c2e564448cbe8a8e6cc5b440e92024-12-14T16:03:56ZengRadcliffe Medical MediaEuropean Cardiology Review1758-37561758-37642022-11-011710.15420/ecr.2022.13Grading of Aortic Stenosis: Is it More Complicated in Women?Dana Cramariuc0Edda Bahlmann1Eva Gerdts2Department of Heart Disease, Haukeland University Hospital, Bergen, Norway; Department of Clinical Science, University of Bergen, Bergen, NorwayDepartment of Cardiology, Asklepios Kliniken St. Georg, Hamburg, GermanyDepartment of Clinical Science, University of Bergen, Bergen, NorwayAortic stenosis (AS) is the most common valvular heart disease and the main indication for valvular replacement in older women. Correct AS grading is mandatory for an adequate selection of patients for both surgical and transcatheter aortic valve replacement. Women and men have different AS severity grades at the same level of aortic valve calcification. Moreover, besides having smaller cardiac volumes, left ventricular outflow tract and aortic size, women have a specific pattern of left ventricular structural and functional remodelling in response to the AS-related chronic pressure overload. Here, the sex-specific cardiac changes in AS that make AS grading more challenging in women, with consequences for the management and outcome of this group of patients, are reviewed.https://www.ecrjournal.com/articleindex/ecr.2022.13
spellingShingle Dana Cramariuc
Edda Bahlmann
Eva Gerdts
Grading of Aortic Stenosis: Is it More Complicated in Women?
European Cardiology Review
title Grading of Aortic Stenosis: Is it More Complicated in Women?
title_full Grading of Aortic Stenosis: Is it More Complicated in Women?
title_fullStr Grading of Aortic Stenosis: Is it More Complicated in Women?
title_full_unstemmed Grading of Aortic Stenosis: Is it More Complicated in Women?
title_short Grading of Aortic Stenosis: Is it More Complicated in Women?
title_sort grading of aortic stenosis is it more complicated in women
url https://www.ecrjournal.com/articleindex/ecr.2022.13
work_keys_str_mv AT danacramariuc gradingofaorticstenosisisitmorecomplicatedinwomen
AT eddabahlmann gradingofaorticstenosisisitmorecomplicatedinwomen
AT evagerdts gradingofaorticstenosisisitmorecomplicatedinwomen