A model of the artificial metastasis of human epidermoid carcinoma A431 in nude mice for examination of the oncolytic activity of vaccinia virus

A model of the artificial metastasis of human epidermoid carcinoma A431 in nude mice for examination of the oncolytic activity of vaccinia virus

Human carcinoma A431 cells were subcutaneously injected into nude mice at points remote from each other. One of the two xenografts developed after­wards was used for treatment with a recombinant vaccinia virus, while another served as an artificial metastasis. We used the attenuated recombinant vacc...

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Bibliographic Details
Main Authors: G. V. Kochneva, A. A. Grazhdantseva, G. F. Sivolobova, A. V. Tkacheva, A. N. Shvalov, A. Yu. Unusova, E. I. Ryabchikova, S. V. Netesov
Format: Article
Language:English
Published: Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2015-12-01
Series:Вавиловский журнал генетики и селекции
Subjects:
recombinant vaccinia virus
human carcinoma a431
xenografts
metastasis model
oncolytic activity
Online Access:https://vavilov.elpub.ru/jour/article/view/439
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