Nutrient deficiency and physical inactivity in middle-aged adults with dynapenia and metabolic syndrome: results from a nationwide survey

Abstract Background This study examined the associations between dynapenia, metabolic syndrome (MetS), nutrient intake, and physical activity. Methods We used data from a cross-sectional study that included middle-aged men and women (40–64 years old) who participated in the Korea National Health and...

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Main Authors: Mijin Kim, Toshiro Kobori
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Nutrition & Metabolism
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Online Access:https://doi.org/10.1186/s12986-025-00978-1
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author Mijin Kim
Toshiro Kobori
author_facet Mijin Kim
Toshiro Kobori
author_sort Mijin Kim
collection DOAJ
description Abstract Background This study examined the associations between dynapenia, metabolic syndrome (MetS), nutrient intake, and physical activity. Methods We used data from a cross-sectional study that included middle-aged men and women (40–64 years old) who participated in the Korea National Health and Nutrition Examination Survey (KNHANES) between 2014 and 2017. Patients (n = 4700) were categorized into four groups based on diagnosis of dynapenia and MetS: dynapenic MetS (DM), dynapenia alone (D), MetS alone (M), and non-dynapenia and non-MetS (NDNM). Dynapenia was defined as the lowest tertile of the BMI-adjusted handgrip strength. MetS was defined as central obesity plus two or more of the following features: elevated fasting plasma glucose, blood pressure, or triglycerides, or reduced HDL cholesterol. Nutrient intake and physical activity were assessed via questionnaires. Results In women, the DM group had a significantly lower intake of all nutrients except for total energy and carbohydrates compared to the NDNM group. In a model adjusted for age, osteoarthritis, and total energy intake, the DM group showed higher odds ratios (ORs) for not practicing resistance training (men: OR (95% confidence intervals (CI)) = 1.64 (1.22–2.20); women: OR (95% CI) = 2.26 (1.59–3.21)) and for engaging in physical activities below 600 metabolic equivalents of tasks per week (men: OR (95% CI) = 1.36 (1.05–1.78); women: OR (95% CI) = 1.29 (1.02–1.63)) than the NDNM group. The women in the DM group had significantly higher OR for leisure-related moderate (OR (95% CI) = 2.00 (1.49–2.68)) and vigorous (OR (95% CI) = 1.76 (1.10–2.82)) physical inactivity than in the NDNM group. Conclusions This study showed that the combination of dynapenia and MetS was associated with poor nutrient intake in women and low physical activity in both sexes. These findings provide a foundation for developing intervention strategies to address dynapenia and MetS.
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spelling doaj-art-291b4c7fcad149959f1908c483404bdc2025-08-20T03:42:37ZengBMCNutrition & Metabolism1743-70752025-08-0122111510.1186/s12986-025-00978-1Nutrient deficiency and physical inactivity in middle-aged adults with dynapenia and metabolic syndrome: results from a nationwide surveyMijin Kim0Toshiro Kobori1Institute of Food Research, National Agriculture and Food Research OrganizationInstitute of Food Research, National Agriculture and Food Research OrganizationAbstract Background This study examined the associations between dynapenia, metabolic syndrome (MetS), nutrient intake, and physical activity. Methods We used data from a cross-sectional study that included middle-aged men and women (40–64 years old) who participated in the Korea National Health and Nutrition Examination Survey (KNHANES) between 2014 and 2017. Patients (n = 4700) were categorized into four groups based on diagnosis of dynapenia and MetS: dynapenic MetS (DM), dynapenia alone (D), MetS alone (M), and non-dynapenia and non-MetS (NDNM). Dynapenia was defined as the lowest tertile of the BMI-adjusted handgrip strength. MetS was defined as central obesity plus two or more of the following features: elevated fasting plasma glucose, blood pressure, or triglycerides, or reduced HDL cholesterol. Nutrient intake and physical activity were assessed via questionnaires. Results In women, the DM group had a significantly lower intake of all nutrients except for total energy and carbohydrates compared to the NDNM group. In a model adjusted for age, osteoarthritis, and total energy intake, the DM group showed higher odds ratios (ORs) for not practicing resistance training (men: OR (95% confidence intervals (CI)) = 1.64 (1.22–2.20); women: OR (95% CI) = 2.26 (1.59–3.21)) and for engaging in physical activities below 600 metabolic equivalents of tasks per week (men: OR (95% CI) = 1.36 (1.05–1.78); women: OR (95% CI) = 1.29 (1.02–1.63)) than the NDNM group. The women in the DM group had significantly higher OR for leisure-related moderate (OR (95% CI) = 2.00 (1.49–2.68)) and vigorous (OR (95% CI) = 1.76 (1.10–2.82)) physical inactivity than in the NDNM group. Conclusions This study showed that the combination of dynapenia and MetS was associated with poor nutrient intake in women and low physical activity in both sexes. These findings provide a foundation for developing intervention strategies to address dynapenia and MetS.https://doi.org/10.1186/s12986-025-00978-1DynapeniaMuscle strengthMetabolic syndromeNutrient intakePhysical activity
spellingShingle Mijin Kim
Toshiro Kobori
Nutrient deficiency and physical inactivity in middle-aged adults with dynapenia and metabolic syndrome: results from a nationwide survey
Nutrition & Metabolism
Dynapenia
Muscle strength
Metabolic syndrome
Nutrient intake
Physical activity
title Nutrient deficiency and physical inactivity in middle-aged adults with dynapenia and metabolic syndrome: results from a nationwide survey
title_full Nutrient deficiency and physical inactivity in middle-aged adults with dynapenia and metabolic syndrome: results from a nationwide survey
title_fullStr Nutrient deficiency and physical inactivity in middle-aged adults with dynapenia and metabolic syndrome: results from a nationwide survey
title_full_unstemmed Nutrient deficiency and physical inactivity in middle-aged adults with dynapenia and metabolic syndrome: results from a nationwide survey
title_short Nutrient deficiency and physical inactivity in middle-aged adults with dynapenia and metabolic syndrome: results from a nationwide survey
title_sort nutrient deficiency and physical inactivity in middle aged adults with dynapenia and metabolic syndrome results from a nationwide survey
topic Dynapenia
Muscle strength
Metabolic syndrome
Nutrient intake
Physical activity
url https://doi.org/10.1186/s12986-025-00978-1
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AT toshirokobori nutrientdeficiencyandphysicalinactivityinmiddleagedadultswithdynapeniaandmetabolicsyndromeresultsfromanationwidesurvey