Colorectal cancer: state-of-the-art

The aim of review. To give analysis to modern concepts of colorectal cancer (CRC).Original positions. CRC is the 2nd most common cause of morbidity after the lung cancer. It includes hereditary non-polyposis CRC (Lynch syndrome), hereditary CRC at familial adenomatosis and sporadic (non-hereditary)...

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Main Author: Ya. S. Tsimmerman
Format: Article
Language:Russian
Published: Gastro LLC 2012-07-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
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Online Access:https://www.gastro-j.ru/jour/article/view/1305
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author Ya. S. Tsimmerman
author_facet Ya. S. Tsimmerman
author_sort Ya. S. Tsimmerman
collection DOAJ
description The aim of review. To give analysis to modern concepts of colorectal cancer (CRC).Original positions. CRC is the 2nd most common cause of morbidity after the lung cancer. It includes hereditary non-polyposis CRC (Lynch syndrome), hereditary CRC at familial adenomatosis and sporadic (non-hereditary) CRC. For each of these categories screening diagnostics programs are developed. At patients with ulcerative colitis the risk of CRC development depends on duration of disease, extent of the large intestine involvement, combination to primary sclerosing cholangitis and presence of blood relatives, affected by CRC.Conclusion. Further studies to reveal causes and mechanisms of premalignant states of the large intestine and CRC are required. Methods of surgical and chemotherapeutic treatment of patients of CRC and its prophylaxis require improvement.
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publishDate 2012-07-01
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record_format Article
series Российский журнал гастроэнтерологии, гепатологии, колопроктологии
spelling doaj-art-290fc4d6c40a40dfb28db10958bf87042025-02-10T16:14:32ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732012-07-01224516877Colorectal cancer: state-of-the-artYa. S. Tsimmerman0Vagner Perm state medical academy of the Ministry of Health and Social Development of RussiaThe aim of review. To give analysis to modern concepts of colorectal cancer (CRC).Original positions. CRC is the 2nd most common cause of morbidity after the lung cancer. It includes hereditary non-polyposis CRC (Lynch syndrome), hereditary CRC at familial adenomatosis and sporadic (non-hereditary) CRC. For each of these categories screening diagnostics programs are developed. At patients with ulcerative colitis the risk of CRC development depends on duration of disease, extent of the large intestine involvement, combination to primary sclerosing cholangitis and presence of blood relatives, affected by CRC.Conclusion. Further studies to reveal causes and mechanisms of premalignant states of the large intestine and CRC are required. Methods of surgical and chemotherapeutic treatment of patients of CRC and its prophylaxis require improvement.https://www.gastro-j.ru/jour/article/view/1305colorectal cancerscreening diagnosticstreatmentprophylaxis
spellingShingle Ya. S. Tsimmerman
Colorectal cancer: state-of-the-art
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
colorectal cancer
screening diagnostics
treatment
prophylaxis
title Colorectal cancer: state-of-the-art
title_full Colorectal cancer: state-of-the-art
title_fullStr Colorectal cancer: state-of-the-art
title_full_unstemmed Colorectal cancer: state-of-the-art
title_short Colorectal cancer: state-of-the-art
title_sort colorectal cancer state of the art
topic colorectal cancer
screening diagnostics
treatment
prophylaxis
url https://www.gastro-j.ru/jour/article/view/1305
work_keys_str_mv AT yastsimmerman colorectalcancerstateoftheart