Colorectal cancer: state-of-the-art
The aim of review. To give analysis to modern concepts of colorectal cancer (CRC).Original positions. CRC is the 2nd most common cause of morbidity after the lung cancer. It includes hereditary non-polyposis CRC (Lynch syndrome), hereditary CRC at familial adenomatosis and sporadic (non-hereditary)...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2012-07-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/1305 |
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| Summary: | The aim of review. To give analysis to modern concepts of colorectal cancer (CRC).Original positions. CRC is the 2nd most common cause of morbidity after the lung cancer. It includes hereditary non-polyposis CRC (Lynch syndrome), hereditary CRC at familial adenomatosis and sporadic (non-hereditary) CRC. For each of these categories screening diagnostics programs are developed. At patients with ulcerative colitis the risk of CRC development depends on duration of disease, extent of the large intestine involvement, combination to primary sclerosing cholangitis and presence of blood relatives, affected by CRC.Conclusion. Further studies to reveal causes and mechanisms of premalignant states of the large intestine and CRC are required. Methods of surgical and chemotherapeutic treatment of patients of CRC and its prophylaxis require improvement. |
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| ISSN: | 1382-4376 2658-6673 |