Galactomannan Downregulates the Inflammation Responses in Human Macrophages via NFκB2/p100

Galactomannan Downregulates the Inflammation Responses in Human Macrophages via NFκB2/p100

We show that galactomannan, a polysaccharide consisting of a mannose backbone with galactose side groups present on the cell wall of several fungi, induces a reprogramming of the inflammatory response in human macrophages through dectin-1 receptor. The nuclear factor kappa-light-chain-enhancer of ac...

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Bibliographic Details
Main Authors:	Víctor Toledano, Enrique Hernández-Jiménez, Carolina Cubillos-Zapata, Marta Flandez, Enrique Álvarez, Aníbal Varela-Serrano, Ramón Cantero, Gema Valles, Francisco García-Rio, Eduardo López-Collazo
Format:	Article
Language:	English
Published:	Wiley 2015-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2015/942517
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