Learning the therapeutic targets of acute myeloid leukemia through multiscale human interactome network and community analysis

Abstract Acute myeloid leukemia (AML) is caused by proliferation of mutated myeloid progenitor cells. The standard chemotherapy regimen does not efficiently cause remission as there is a high relapse rate. Resistance acquired by leukemic stem cells is suggested to be one of the root causes of relaps...

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Bibliographic Details
Main Authors: Suruthy Sivanathan, Ting Hu
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BioData Mining
Subjects:
Online Access:https://doi.org/10.1186/s13040-025-00444-x
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