Double Pump Sequential Constant Citrate Anticoagulation in General Hemodialysis
Objective. To investigate the safety and efficacy of single-pump and double-pump sequential anticoagulation in general hemodialysis under the condition of constant citrate. Methods. A total of 32 patients with end-stage renal disease complicated with hemorrhage admitted by Zigong Third People’s Hosp...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Applied Bionics and Biomechanics |
| Online Access: | http://dx.doi.org/10.1155/2022/6047074 |
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| _version_ | 1850230545528651776 |
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| author | Li Tang Jiali Zhang Qijun Cheng Jie Li Ling Zhou Li Wang Changbin Liao |
| author_facet | Li Tang Jiali Zhang Qijun Cheng Jie Li Ling Zhou Li Wang Changbin Liao |
| author_sort | Li Tang |
| collection | DOAJ |
| description | Objective. To investigate the safety and efficacy of single-pump and double-pump sequential anticoagulation in general hemodialysis under the condition of constant citrate. Methods. A total of 32 patients with end-stage renal disease complicated with hemorrhage admitted by Zigong Third People’s Hospital from December 2019 to December 2020 were collected. Randomly divided into single pump group (n=17) and double pump group (n=15). The coagulation of dialyzer and intravenous pot was compared between the two groups. Then, the changes of serum calcium before treatment, after 2 h treatment, and after the completion of the treatment, and the front of the blood pump and intravenous pot, as well as behind the intravenous pot were observed and recorded in the two groups. Then, single-pool clearance of urea/volume (spKt/V) was compared between the two groups. Results. There were few differences in dialyzer coagulation between the single pump group and double pump group. However, the single pump group had a significant increase in the number of intravenous pot coagulations than the double pump group. At 2 h for dialysis, the serum calcium level behind the intravenous pot in the double pump group was notably lower than that in the single pump group. And after the completion of dialysis, the serum calcium returned to pretreatment level. The Kt/v in both groups reached the normal standard without statistically significant difference. And there were no adverse reactions in the patients of both groups after dialysis. Conclusion. For hemodialysis patients with bleeding, dual-pump segmented anticoagulation is superior to single-pump anticoagulation in intravenous pot anticoagulation. Double pump segmented sequential constant citrate anticoagulation can be utilized as a new simple and effective anticoagulation method for clinical hemodialysis. |
| format | Article |
| id | doaj-art-29068cd3969c443abb7961bf592e3ba9 |
| institution | OA Journals |
| issn | 1754-2103 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Applied Bionics and Biomechanics |
| spelling | doaj-art-29068cd3969c443abb7961bf592e3ba92025-08-20T02:03:51ZengWileyApplied Bionics and Biomechanics1754-21032022-01-01202210.1155/2022/6047074Double Pump Sequential Constant Citrate Anticoagulation in General HemodialysisLi Tang0Jiali Zhang1Qijun Cheng2Jie Li3Ling Zhou4Li Wang5Changbin Liao6Zigong Third People’s HospitalZigong Third People’s HospitalZigong First People’s HospitalZigong Third People’s HospitalZigong Third People’s HospitalZigong Third People’s HospitalZigong Third People’s HospitalObjective. To investigate the safety and efficacy of single-pump and double-pump sequential anticoagulation in general hemodialysis under the condition of constant citrate. Methods. A total of 32 patients with end-stage renal disease complicated with hemorrhage admitted by Zigong Third People’s Hospital from December 2019 to December 2020 were collected. Randomly divided into single pump group (n=17) and double pump group (n=15). The coagulation of dialyzer and intravenous pot was compared between the two groups. Then, the changes of serum calcium before treatment, after 2 h treatment, and after the completion of the treatment, and the front of the blood pump and intravenous pot, as well as behind the intravenous pot were observed and recorded in the two groups. Then, single-pool clearance of urea/volume (spKt/V) was compared between the two groups. Results. There were few differences in dialyzer coagulation between the single pump group and double pump group. However, the single pump group had a significant increase in the number of intravenous pot coagulations than the double pump group. At 2 h for dialysis, the serum calcium level behind the intravenous pot in the double pump group was notably lower than that in the single pump group. And after the completion of dialysis, the serum calcium returned to pretreatment level. The Kt/v in both groups reached the normal standard without statistically significant difference. And there were no adverse reactions in the patients of both groups after dialysis. Conclusion. For hemodialysis patients with bleeding, dual-pump segmented anticoagulation is superior to single-pump anticoagulation in intravenous pot anticoagulation. Double pump segmented sequential constant citrate anticoagulation can be utilized as a new simple and effective anticoagulation method for clinical hemodialysis.http://dx.doi.org/10.1155/2022/6047074 |
| spellingShingle | Li Tang Jiali Zhang Qijun Cheng Jie Li Ling Zhou Li Wang Changbin Liao Double Pump Sequential Constant Citrate Anticoagulation in General Hemodialysis Applied Bionics and Biomechanics |
| title | Double Pump Sequential Constant Citrate Anticoagulation in General Hemodialysis |
| title_full | Double Pump Sequential Constant Citrate Anticoagulation in General Hemodialysis |
| title_fullStr | Double Pump Sequential Constant Citrate Anticoagulation in General Hemodialysis |
| title_full_unstemmed | Double Pump Sequential Constant Citrate Anticoagulation in General Hemodialysis |
| title_short | Double Pump Sequential Constant Citrate Anticoagulation in General Hemodialysis |
| title_sort | double pump sequential constant citrate anticoagulation in general hemodialysis |
| url | http://dx.doi.org/10.1155/2022/6047074 |
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