The effect of the APOE4 genotype on physiological and cognitive health in randomised controlled trials with an exercise intervention: a systematic review and meta-analysis

The effect of the APOE4 genotype on physiological and cognitive health in randomised controlled trials with an exercise intervention: a systematic review and meta-analysis

Abstract Background Alzheimer’s disease is caused by modifiable and non-modifiable risk factors. Randomised controlled trials have investigated whether the strongest genetic risk factor for Alzheimer’s disease, APOE4, impacts the effectiveness of exercise on health. Systematic reviews are yet to eva...

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Bibliographic Details
Main Authors:	Felicity S. E. Spencer, Richard J. Elsworthy, Leigh Breen, Jon R. B. Bishop, Connor Dunleavy, Sarah Aldred
Format:	Article
Language:	English
Published:	BMC 2025-01-01
Series:	Trials
Subjects:	Exercise Alzheimer’s disease Randomised controlled trials
Online Access:	https://doi.org/10.1186/s13063-024-08696-4
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