Efficacy and safety of anlotinib in combination with ¹³¹I therapy in the treatment of distant metastatic differentiated thyroid cancer: a single-arm, phase II study

Efficacy and safety of anlotinib in combination with ¹³¹I therapy in the treatment of distant metastatic differentiated thyroid cancer: a single-arm, phase II study

BackgroundRadioactive iodine (RAI) is the standard treatment for distant metastatic differentiated thyroid cancer (dmDTC). However, many patients fail to achieve satisfactory effects and prognosis. Anlotinib is a highly effective antiangiogenic tyrosine kinase inhibitor (TKI) that has shown promisin...

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Bibliographic Details
Main Authors: Yan Li, Jianjing Liu, Qian Su, Xueyao Liu, Zhen Yang, Zhao Yang, Jie Fu, Yan Zhang, Lina Tong, Fang Yang, Dong Dai
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
anlotinib
131I therapy
distant metastatic differentiated thyroid cancer
efficacy
safety
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1622676/full
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