Radionuclide semiotics of pulmonary hypertension and NO production in children with non-cyanotic heart valve disease

Radionuclide assessment of pulmonary hemodynamics was performed in 45 children with congenital heart valve pathology and increased pulmonary blood flow. Radionuclide angiopulmonography was performed at rest and during acute pharmacological tests, before and after valve surgery. Basal and enalapril-s...

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Bibliographic Details
Main Authors: Yu. B. Lishmanov, K. V. Zavadovsky, S. N. Ivanov, T. E. Suslova
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2005-10-01
Series:Российский кардиологический журнал
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Online Access:https://russjcardiol.elpub.ru/jour/article/view/2353
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Summary:Radionuclide assessment of pulmonary hemodynamics was performed in 45 children with congenital heart valve pathology and increased pulmonary blood flow. Radionuclide angiopulmonography was performed at rest and during acute pharmacological tests, before and after valve surgery. Basal and enalapril-stimulated plasma concentrations of stable NO metabolites (nitrite and nitrate anions) were measured. Radionuclide bolus speed dynamics after vasodilatator (niphedipine, enalapril) administration demonstrated pulmonary circulation reserve. Plasma levels of NO metabolites were used in erectile dysfunction verification.
ISSN:1560-4071
2618-7620