Interleukin-10 gene polymorphism in patients with systemic lupus erythematosus and normal individuals of Kasakh population
An analysis of interleukin-10 (IL-10) gene polymorphism associative link with clinical variability in Kasakhs. 49 pts with systemic lupus erythematosus were included (48 female and I male). Promotive IL-10 gene region determined by a point variable in 627 locus was assessed with restrict fragment le...
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| Format: | Article |
| Language: | Russian |
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IMA PRESS LLC
2003-08-01
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| Series: | Научно-практическая ревматология |
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| Online Access: | https://rsp.mediar-press.net/rsp/article/view/1207 |
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| author | Z E Omarbekova R L Ivanova I A Guseva V A Myakotkin |
| author_facet | Z E Omarbekova R L Ivanova I A Guseva V A Myakotkin |
| author_sort | Z E Omarbekova |
| collection | DOAJ |
| description | An analysis of interleukin-10 (IL-10) gene polymorphism associative link with clinical variability in Kasakhs. 49 pts with systemic lupus erythematosus were included (48 female and I male). Promotive IL-10 gene region determined by a point variable in 627 locus was assessed with restrict fragment length polymorphism method using restrictase Rsal. The results showed allele IL-10 gene polymorphism significance in disease risk determination, clinical variability and features of pathological process course in Kasakhs. |
| format | Article |
| id | doaj-art-28fe26da03e44877ac1f2fdae7fc92c8 |
| institution | Kabale University |
| issn | 1995-4484 1995-4492 |
| language | Russian |
| publishDate | 2003-08-01 |
| publisher | IMA PRESS LLC |
| record_format | Article |
| series | Научно-практическая ревматология |
| spelling | doaj-art-28fe26da03e44877ac1f2fdae7fc92c82025-08-20T03:38:34ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922003-08-01414303210.14412/1995-4484-2003-13291147Interleukin-10 gene polymorphism in patients with systemic lupus erythematosus and normal individuals of Kasakh populationZ E OmarbekovaR L IvanovaI A GusevaV A MyakotkinAn analysis of interleukin-10 (IL-10) gene polymorphism associative link with clinical variability in Kasakhs. 49 pts with systemic lupus erythematosus were included (48 female and I male). Promotive IL-10 gene region determined by a point variable in 627 locus was assessed with restrict fragment length polymorphism method using restrictase Rsal. The results showed allele IL-10 gene polymorphism significance in disease risk determination, clinical variability and features of pathological process course in Kasakhs.https://rsp.mediar-press.net/rsp/article/view/1207il-10genetic heterogeneityclinical polymorphismsystemic lupus erythematosus |
| spellingShingle | Z E Omarbekova R L Ivanova I A Guseva V A Myakotkin Interleukin-10 gene polymorphism in patients with systemic lupus erythematosus and normal individuals of Kasakh population Научно-практическая ревматология il-10 genetic heterogeneity clinical polymorphism systemic lupus erythematosus |
| title | Interleukin-10 gene polymorphism in patients with systemic lupus erythematosus and normal individuals of Kasakh population |
| title_full | Interleukin-10 gene polymorphism in patients with systemic lupus erythematosus and normal individuals of Kasakh population |
| title_fullStr | Interleukin-10 gene polymorphism in patients with systemic lupus erythematosus and normal individuals of Kasakh population |
| title_full_unstemmed | Interleukin-10 gene polymorphism in patients with systemic lupus erythematosus and normal individuals of Kasakh population |
| title_short | Interleukin-10 gene polymorphism in patients with systemic lupus erythematosus and normal individuals of Kasakh population |
| title_sort | interleukin 10 gene polymorphism in patients with systemic lupus erythematosus and normal individuals of kasakh population |
| topic | il-10 genetic heterogeneity clinical polymorphism systemic lupus erythematosus |
| url | https://rsp.mediar-press.net/rsp/article/view/1207 |
| work_keys_str_mv | AT zeomarbekova interleukin10genepolymorphisminpatientswithsystemiclupuserythematosusandnormalindividualsofkasakhpopulation AT rlivanova interleukin10genepolymorphisminpatientswithsystemiclupuserythematosusandnormalindividualsofkasakhpopulation AT iaguseva interleukin10genepolymorphisminpatientswithsystemiclupuserythematosusandnormalindividualsofkasakhpopulation AT vamyakotkin interleukin10genepolymorphisminpatientswithsystemiclupuserythematosusandnormalindividualsofkasakhpopulation |