Inflammatory Bowel Disease in Children of Middle Eastern Descent
Increasing rates of inflammatory bowel disease (IBD) are now seen in populations where it was once uncommon. The pattern of IBD in children of Middle Eastern descent in Australia has never been reported. This study aimed to investigate the burden of IBD in children of Middle Eastern descent at the S...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | International Journal of Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2014/906128 |
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| _version_ | 1832561823674531840 |
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| author | Christina Mai Ying Naidoo Steven T. Leach Andrew S. Day Daniel A. Lemberg |
| author_facet | Christina Mai Ying Naidoo Steven T. Leach Andrew S. Day Daniel A. Lemberg |
| author_sort | Christina Mai Ying Naidoo |
| collection | DOAJ |
| description | Increasing rates of inflammatory bowel disease (IBD) are now seen in populations where it was once uncommon. The pattern of IBD in children of Middle Eastern descent in Australia has never been reported. This study aimed to investigate the burden of IBD in children of Middle Eastern descent at the Sydney Children’s Hospital, Randwick (SCHR). The SCHR IBD database was used to identify patients of self-reported Middle Eastern ethnicity diagnosed between 1987 and 2011. Demographic, diagnosis, and management data was collected for all Middle Eastern children and an age and gender matched non-Middle Eastern IBD control group. Twenty-four patients of Middle Eastern descent were identified. Middle Eastern Crohn’s disease patients had higher disease activity at diagnosis, higher use of thiopurines, and less restricted colonic disease than controls. Although there were limitations with this dataset, we estimated a higher prevalence of IBD in Middle Eastern children and they had a different disease phenotype and behavior compared to the control group, with less disease restricted to the colon and likely a more active disease course. |
| format | Article |
| id | doaj-art-28fb77d0b385412dae36f1913fdfa4ea |
| institution | Kabale University |
| issn | 1687-9740 1687-9759 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Pediatrics |
| spelling | doaj-art-28fb77d0b385412dae36f1913fdfa4ea2025-02-03T01:24:00ZengWileyInternational Journal of Pediatrics1687-97401687-97592014-01-01201410.1155/2014/906128906128Inflammatory Bowel Disease in Children of Middle Eastern DescentChristina Mai Ying Naidoo0Steven T. Leach1Andrew S. Day2Daniel A. Lemberg3School of Women’s and Children’s Health, University of New South Wales, Sydney, NSW 2052, AustraliaSchool of Women’s and Children’s Health, University of New South Wales, Sydney, NSW 2052, AustraliaSchool of Women’s and Children’s Health, University of New South Wales, Sydney, NSW 2052, AustraliaSchool of Women’s and Children’s Health, University of New South Wales, Sydney, NSW 2052, AustraliaIncreasing rates of inflammatory bowel disease (IBD) are now seen in populations where it was once uncommon. The pattern of IBD in children of Middle Eastern descent in Australia has never been reported. This study aimed to investigate the burden of IBD in children of Middle Eastern descent at the Sydney Children’s Hospital, Randwick (SCHR). The SCHR IBD database was used to identify patients of self-reported Middle Eastern ethnicity diagnosed between 1987 and 2011. Demographic, diagnosis, and management data was collected for all Middle Eastern children and an age and gender matched non-Middle Eastern IBD control group. Twenty-four patients of Middle Eastern descent were identified. Middle Eastern Crohn’s disease patients had higher disease activity at diagnosis, higher use of thiopurines, and less restricted colonic disease than controls. Although there were limitations with this dataset, we estimated a higher prevalence of IBD in Middle Eastern children and they had a different disease phenotype and behavior compared to the control group, with less disease restricted to the colon and likely a more active disease course.http://dx.doi.org/10.1155/2014/906128 |
| spellingShingle | Christina Mai Ying Naidoo Steven T. Leach Andrew S. Day Daniel A. Lemberg Inflammatory Bowel Disease in Children of Middle Eastern Descent International Journal of Pediatrics |
| title | Inflammatory Bowel Disease in Children of Middle Eastern Descent |
| title_full | Inflammatory Bowel Disease in Children of Middle Eastern Descent |
| title_fullStr | Inflammatory Bowel Disease in Children of Middle Eastern Descent |
| title_full_unstemmed | Inflammatory Bowel Disease in Children of Middle Eastern Descent |
| title_short | Inflammatory Bowel Disease in Children of Middle Eastern Descent |
| title_sort | inflammatory bowel disease in children of middle eastern descent |
| url | http://dx.doi.org/10.1155/2014/906128 |
| work_keys_str_mv | AT christinamaiyingnaidoo inflammatoryboweldiseaseinchildrenofmiddleeasterndescent AT steventleach inflammatoryboweldiseaseinchildrenofmiddleeasterndescent AT andrewsday inflammatoryboweldiseaseinchildrenofmiddleeasterndescent AT danielalemberg inflammatoryboweldiseaseinchildrenofmiddleeasterndescent |