Mechanical thrombextraction in patient with acute ischemic stroke on background of oral anticoagulant therapy
Thrombolytic therapy, which is a priority treatment strategy in patients with acute ischemic stroke in the first 3-4.5 hours after start of the disease, has significant limitations in case of background anticoagulant therapy. Mechanic thrombextraction is considered to be an alternative therapeutic s...
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| Format: | Article |
| Language: | English |
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TOV Chetverta Khvylia
2021-03-01
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| Series: | Кардіохірургія та інтервенційна кардіологія |
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| Online Access: | http://www.csic.com.ua/images/pdf/2021/1-2021/mechanical-thrombextraction-patient-with-acute-ischemic-stroke-background-oral-anticoagulant-therapy.pdf |
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| author | V.О. Yarosh V.V. Babenko O.E. Svyrydiuk O.J. Zharinov O.A. Yepanchintseva B.M. Todurov |
| author_facet | V.О. Yarosh V.V. Babenko O.E. Svyrydiuk O.J. Zharinov O.A. Yepanchintseva B.M. Todurov |
| author_sort | V.О. Yarosh |
| collection | DOAJ |
| description | Thrombolytic therapy, which is a priority treatment strategy in patients with acute ischemic stroke in the first 3-4.5 hours after start of the disease, has significant limitations in case of background anticoagulant therapy. Mechanic thrombextraction is considered to be an alternative therapeutic strategy in case of inefficacy or contraindications to thrombolytic therapy. The article presents a clinical case of the 75-year old female patient with acute cardioembolic stroke on background of heart failure and atrial fibrillation. Long-term background usage of the direct oral anticoagulant due to atrial fibrillation is a limitation to use thrombolytic therapy, therefore mechanical thrombextraction was performed. The case presents possibilities of the successful interventional treatment of acute cardioembolic ischemic stroke. An example of a possible drug-drug interaction possibly leading to reduction of the effectiveness of anticoagulant therapy is shown. |
| format | Article |
| id | doaj-art-28f2e000a282465382c0069541bdce92 |
| institution | Kabale University |
| issn | 2305-3127 |
| language | English |
| publishDate | 2021-03-01 |
| publisher | TOV Chetverta Khvylia |
| record_format | Article |
| series | Кардіохірургія та інтервенційна кардіологія |
| spelling | doaj-art-28f2e000a282465382c0069541bdce922025-02-02T21:03:50ZengTOV Chetverta KhvyliaКардіохірургія та інтервенційна кардіологія2305-31272021-03-011364010.31928/2305-3127-2021.1.3640Mechanical thrombextraction in patient with acute ischemic stroke on background of oral anticoagulant therapyV.О. Yarosh0V.V. Babenko1O.E. Svyrydiuk2O.J. Zharinov3O.A. Yepanchintseva4B.M. Todurov5Heart Institute, Ministry of Health of Ukraine, Kyiv, UkraineHeart Institute, Ministry of Health of Ukraine, Kyiv, UkraineScientific-Practical Center of Endovascular Neuroradiology of NAMS of Ukraine, Kyiv, UkraineShupyk National Medical Academy of Postgraduate Education, Kyiv, UkraineHeart Institute, Ministry of Health of Ukraine, Kyiv, Ukraine, Shupyk National Medical Academy of Postgraduate Education, Kyiv, UkraineHeart Institute, Ministry of Health of Ukraine, Kyiv, Ukraine, Shupyk National Medical Academy of Postgraduate Education, Kyiv, UkraineThrombolytic therapy, which is a priority treatment strategy in patients with acute ischemic stroke in the first 3-4.5 hours after start of the disease, has significant limitations in case of background anticoagulant therapy. Mechanic thrombextraction is considered to be an alternative therapeutic strategy in case of inefficacy or contraindications to thrombolytic therapy. The article presents a clinical case of the 75-year old female patient with acute cardioembolic stroke on background of heart failure and atrial fibrillation. Long-term background usage of the direct oral anticoagulant due to atrial fibrillation is a limitation to use thrombolytic therapy, therefore mechanical thrombextraction was performed. The case presents possibilities of the successful interventional treatment of acute cardioembolic ischemic stroke. An example of a possible drug-drug interaction possibly leading to reduction of the effectiveness of anticoagulant therapy is shown.http://www.csic.com.ua/images/pdf/2021/1-2021/mechanical-thrombextraction-patient-with-acute-ischemic-stroke-background-oral-anticoagulant-therapy.pdfischemic strokeanticoagulantsmechanical trombextraction |
| spellingShingle | V.О. Yarosh V.V. Babenko O.E. Svyrydiuk O.J. Zharinov O.A. Yepanchintseva B.M. Todurov Mechanical thrombextraction in patient with acute ischemic stroke on background of oral anticoagulant therapy Кардіохірургія та інтервенційна кардіологія ischemic stroke anticoagulants mechanical trombextraction |
| title | Mechanical thrombextraction in patient with acute ischemic stroke on background of oral anticoagulant therapy |
| title_full | Mechanical thrombextraction in patient with acute ischemic stroke on background of oral anticoagulant therapy |
| title_fullStr | Mechanical thrombextraction in patient with acute ischemic stroke on background of oral anticoagulant therapy |
| title_full_unstemmed | Mechanical thrombextraction in patient with acute ischemic stroke on background of oral anticoagulant therapy |
| title_short | Mechanical thrombextraction in patient with acute ischemic stroke on background of oral anticoagulant therapy |
| title_sort | mechanical thrombextraction in patient with acute ischemic stroke on background of oral anticoagulant therapy |
| topic | ischemic stroke anticoagulants mechanical trombextraction |
| url | http://www.csic.com.ua/images/pdf/2021/1-2021/mechanical-thrombextraction-patient-with-acute-ischemic-stroke-background-oral-anticoagulant-therapy.pdf |
| work_keys_str_mv | AT voyarosh mechanicalthrombextractioninpatientwithacuteischemicstrokeonbackgroundoforalanticoagulanttherapy AT vvbabenko mechanicalthrombextractioninpatientwithacuteischemicstrokeonbackgroundoforalanticoagulanttherapy AT oesvyrydiuk mechanicalthrombextractioninpatientwithacuteischemicstrokeonbackgroundoforalanticoagulanttherapy AT ojzharinov mechanicalthrombextractioninpatientwithacuteischemicstrokeonbackgroundoforalanticoagulanttherapy AT oayepanchintseva mechanicalthrombextractioninpatientwithacuteischemicstrokeonbackgroundoforalanticoagulanttherapy AT bmtodurov mechanicalthrombextractioninpatientwithacuteischemicstrokeonbackgroundoforalanticoagulanttherapy |