MER4 endogenous retrovirus correlated with better efficacy of anti-PD1/PD-L1 therapy in non-small cell lung cancer
Background Endogenous retroviruses (ERVs) are highly expressed in various cancer types and are associated with increased innate immune response and better efficacy of antiprogrammed death-1/ligand-1 (anti-PD1/PD-L1)-directed immune checkpoint inhibitors (ICI) in preclinical models. However, their ro...
Saved in:
| Main Authors: | Francois Ghiringhelli, Romain Boidot, Caroline Truntzer, Bertrand Routy, Philippe Joubert, Julie Lecuelle, Laure Favier, Cléa Fraisse, Aurélie Lagrange, Coureche Kaderbhai, Sandy Chevrier |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2022-03-01
|
| Series: | Journal for ImmunoTherapy of Cancer |
| Online Access: | https://jitc.bmj.com/content/10/3/e004241.full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Xenotransplantation and Porcine Endogenous Retroviruses
by: Joachim Denner
Published: (2024-10-01) -
Transactivation of Human Endogenous Retroviruses by Viruses
by: Erin F. Evans, et al.
Published: (2024-10-01) -
Endogenous retroviruses of non-avian/mammalian vertebrates illuminate diversity and deep history of retroviruses.
by: Xiaoyu Xu, et al.
Published: (2018-06-01) -
In-depth analysis of endogenous retrovirus expression in glioblastoma
by: Daniel A. Murimi-Worstell, et al.
Published: (2025-07-01) -
piRNA Defense Against Endogenous Retroviruses
by: Milky Abajorga, et al.
Published: (2024-11-01)