Cerebral Sinovenous Thrombosis in a Child with Idiopathic Nephrotic Syndrome
Nephrotic syndrome (NS) is a renal disorder characterized by heavy proteinuria, hypoalbuninemia, edema and hypercholesterolemia. Nephrotic syndrome in children is known to be associated with an hypercoagulable state and thromboembolic complications. However cerebral sinovenous thrombosis (CSVT) is v...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2011/724950 |
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| author | L. Ghedira Besbes S. Haddad A. Gabsi M. Hassine Ch. Ben Meriem M. N. Guediche |
| author_facet | L. Ghedira Besbes S. Haddad A. Gabsi M. Hassine Ch. Ben Meriem M. N. Guediche |
| author_sort | L. Ghedira Besbes |
| collection | DOAJ |
| description | Nephrotic syndrome (NS) is a renal disorder characterized by heavy proteinuria, hypoalbuninemia, edema and hypercholesterolemia. Nephrotic syndrome in children is known to be associated with an hypercoagulable state and thromboembolic complications. However cerebral sinovenous thrombosis (CSVT) is very rare. Here we report a seven-year-old child with steroid-dependent idopathic nephrotic syndrome resulting from a minimal change disease, developed multiple cerebral sinovenous thrombosis, presenting with headache, left sixth nerve palsy, and papilledema. The diagnosis of CSVT was established by cranial computed tomography, magnetic resonance imaging, and magnetic resonance angiography. He gradually recovered after anticoagulant therapy. CSVT is very rare in nephrotic children. The diagnosis of CSVT should be considered in any patient with nephrotic syndrome who develops neurologic symptoms. This report highlights the importance of suspecting and recognizing this potentially life threatening complication and initiating early treatment. |
| format | Article |
| id | doaj-art-28ea71a8515a478e80ac926a8d5bf7c8 |
| institution | Kabale University |
| issn | 2090-6641 2090-665X |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Nephrology |
| spelling | doaj-art-28ea71a8515a478e80ac926a8d5bf7c82025-08-20T03:54:47ZengWileyCase Reports in Nephrology2090-66412090-665X2011-01-01201110.1155/2011/724950724950Cerebral Sinovenous Thrombosis in a Child with Idiopathic Nephrotic SyndromeL. Ghedira Besbes0S. Haddad1A. Gabsi2M. Hassine3Ch. Ben Meriem4M. N. Guediche5Pediatric Department, Fattouma Bourguiba Hospital, Monastir 5000, TunisiaPediatric Department, Fattouma Bourguiba Hospital, Monastir 5000, TunisiaPediatric Department, Fattouma Bourguiba Hospital, Monastir 5000, TunisiaHematology Laboratory, Fattouma Bourguiba Hospital, Monastir 5000, TunisiaPediatric Department, Fattouma Bourguiba Hospital, Monastir 5000, TunisiaPediatric Department, Fattouma Bourguiba Hospital, Monastir 5000, TunisiaNephrotic syndrome (NS) is a renal disorder characterized by heavy proteinuria, hypoalbuninemia, edema and hypercholesterolemia. Nephrotic syndrome in children is known to be associated with an hypercoagulable state and thromboembolic complications. However cerebral sinovenous thrombosis (CSVT) is very rare. Here we report a seven-year-old child with steroid-dependent idopathic nephrotic syndrome resulting from a minimal change disease, developed multiple cerebral sinovenous thrombosis, presenting with headache, left sixth nerve palsy, and papilledema. The diagnosis of CSVT was established by cranial computed tomography, magnetic resonance imaging, and magnetic resonance angiography. He gradually recovered after anticoagulant therapy. CSVT is very rare in nephrotic children. The diagnosis of CSVT should be considered in any patient with nephrotic syndrome who develops neurologic symptoms. This report highlights the importance of suspecting and recognizing this potentially life threatening complication and initiating early treatment.http://dx.doi.org/10.1155/2011/724950 |
| spellingShingle | L. Ghedira Besbes S. Haddad A. Gabsi M. Hassine Ch. Ben Meriem M. N. Guediche Cerebral Sinovenous Thrombosis in a Child with Idiopathic Nephrotic Syndrome Case Reports in Nephrology |
| title | Cerebral Sinovenous Thrombosis in a Child with Idiopathic Nephrotic Syndrome |
| title_full | Cerebral Sinovenous Thrombosis in a Child with Idiopathic Nephrotic Syndrome |
| title_fullStr | Cerebral Sinovenous Thrombosis in a Child with Idiopathic Nephrotic Syndrome |
| title_full_unstemmed | Cerebral Sinovenous Thrombosis in a Child with Idiopathic Nephrotic Syndrome |
| title_short | Cerebral Sinovenous Thrombosis in a Child with Idiopathic Nephrotic Syndrome |
| title_sort | cerebral sinovenous thrombosis in a child with idiopathic nephrotic syndrome |
| url | http://dx.doi.org/10.1155/2011/724950 |
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