Associations between Personal Exposure to Metals in Fine Particulate Matter and Autonomic Nervous System Dysfunction among Healthy Adults
Abstract The impact of airborne particulate matter and its metal components on autonomic nervous system (ANS) dysfunction in healthy subjects remains unclear. The aim of this study was to examine the effects of personal exposure to airborne particulate matter on the ANS in young, healthy adults. Thi...
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| Format: | Article |
| Language: | English |
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Springer
2024-12-01
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| Series: | Aerosol and Air Quality Research |
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| Online Access: | https://doi.org/10.4209/aaqr.2020.04.0156 |
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| author | Yi-Hsueh Liao Wei-Liang Chen Chung-Ching Wang Ching-Huang Lai |
| author_facet | Yi-Hsueh Liao Wei-Liang Chen Chung-Ching Wang Ching-Huang Lai |
| author_sort | Yi-Hsueh Liao |
| collection | DOAJ |
| description | Abstract The impact of airborne particulate matter and its metal components on autonomic nervous system (ANS) dysfunction in healthy subjects remains unclear. The aim of this study was to examine the effects of personal exposure to airborne particulate matter on the ANS in young, healthy adults. This longitudinal study recruited 82 adults aged 20 to 35 years from districts A and B. District A had lower ambient PM2.5 levels than district B. Personal exposure to fine particulate matter and metals in PM2.5 was collected every two months. The heart rate variability (HRV) indices of each participant were measured three times. The relationship among the PM2.5 concentration, metals in PM2.5 and HRV level was investigated by a generalized estimating equation with an autoregression of order 1. The average age of the participants was 26.4 ± 3.6 years in district A and 21.9 ± 1.5 years in district B (p < 0.001). After adjusting for covariables, significant changes in Log10 standard deviation of normal to normal (SDNN) intervals and Log10 square root of the mean of the sum of the squares of differences (r-MSSDs) were related to unit changes in Log10 iron in PM2.5 (β = −0.033, 95% CI = −0.060 to -0.0056, p < 0.05 and β = −0.041, 95% CI = −0.075 to −0.0076, p < 0.05, respectively). The Log10 SDNN levels were significantly positively related to Log10 gallium in PM2.5 (β = 0.054, 95% CI = 0.0064 to 0.10, p < 0.05). Exposure to heavy metals in airborne particulate matter was associated with ANS dysfunction. |
| format | Article |
| id | doaj-art-28dcc2e88e07490eb3fef3bc3352cec1 |
| institution | Kabale University |
| issn | 1680-8584 2071-1409 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Springer |
| record_format | Article |
| series | Aerosol and Air Quality Research |
| spelling | doaj-art-28dcc2e88e07490eb3fef3bc3352cec12025-02-09T12:19:26ZengSpringerAerosol and Air Quality Research1680-85842071-14092024-12-012081842184910.4209/aaqr.2020.04.0156Associations between Personal Exposure to Metals in Fine Particulate Matter and Autonomic Nervous System Dysfunction among Healthy AdultsYi-Hsueh Liao0Wei-Liang Chen1Chung-Ching Wang2Ching-Huang Lai3Department of Family Medicine, Shuang Ho Hospital, Taipei Medical UniversityDivision of Family Medicine, Department of Family and Community Medicine, Tri-Service General HospitalDivision of Family Medicine, Department of Family and Community Medicine, Tri-Service General HospitalSchool of Public Health, National Defense Medical CenterAbstract The impact of airborne particulate matter and its metal components on autonomic nervous system (ANS) dysfunction in healthy subjects remains unclear. The aim of this study was to examine the effects of personal exposure to airborne particulate matter on the ANS in young, healthy adults. This longitudinal study recruited 82 adults aged 20 to 35 years from districts A and B. District A had lower ambient PM2.5 levels than district B. Personal exposure to fine particulate matter and metals in PM2.5 was collected every two months. The heart rate variability (HRV) indices of each participant were measured three times. The relationship among the PM2.5 concentration, metals in PM2.5 and HRV level was investigated by a generalized estimating equation with an autoregression of order 1. The average age of the participants was 26.4 ± 3.6 years in district A and 21.9 ± 1.5 years in district B (p < 0.001). After adjusting for covariables, significant changes in Log10 standard deviation of normal to normal (SDNN) intervals and Log10 square root of the mean of the sum of the squares of differences (r-MSSDs) were related to unit changes in Log10 iron in PM2.5 (β = −0.033, 95% CI = −0.060 to -0.0056, p < 0.05 and β = −0.041, 95% CI = −0.075 to −0.0076, p < 0.05, respectively). The Log10 SDNN levels were significantly positively related to Log10 gallium in PM2.5 (β = 0.054, 95% CI = 0.0064 to 0.10, p < 0.05). Exposure to heavy metals in airborne particulate matter was associated with ANS dysfunction.https://doi.org/10.4209/aaqr.2020.04.0156Particulate matterMetalsAutonomic nervous system |
| spellingShingle | Yi-Hsueh Liao Wei-Liang Chen Chung-Ching Wang Ching-Huang Lai Associations between Personal Exposure to Metals in Fine Particulate Matter and Autonomic Nervous System Dysfunction among Healthy Adults Aerosol and Air Quality Research Particulate matter Metals Autonomic nervous system |
| title | Associations between Personal Exposure to Metals in Fine Particulate Matter and Autonomic Nervous System Dysfunction among Healthy Adults |
| title_full | Associations between Personal Exposure to Metals in Fine Particulate Matter and Autonomic Nervous System Dysfunction among Healthy Adults |
| title_fullStr | Associations between Personal Exposure to Metals in Fine Particulate Matter and Autonomic Nervous System Dysfunction among Healthy Adults |
| title_full_unstemmed | Associations between Personal Exposure to Metals in Fine Particulate Matter and Autonomic Nervous System Dysfunction among Healthy Adults |
| title_short | Associations between Personal Exposure to Metals in Fine Particulate Matter and Autonomic Nervous System Dysfunction among Healthy Adults |
| title_sort | associations between personal exposure to metals in fine particulate matter and autonomic nervous system dysfunction among healthy adults |
| topic | Particulate matter Metals Autonomic nervous system |
| url | https://doi.org/10.4209/aaqr.2020.04.0156 |
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