Mesenchymal stromal/stem cell-derived exosomes as a potential therapeutic approach to osteoarthritis combined with type 2 diabetes mellitus

Mesenchymal stromal/stem cell-derived exosomes as a potential therapeutic approach to osteoarthritis combined with type 2 diabetes mellitus

Osteoarthritis (OA) and type 2 diabetes mellitus (T2DM) often coexist due to shared risk factors and high prevalence, but effective treatment methods are currently lacking. Mesenchymal stromal/stem cell-derived exosomes (MSC-Exos) have regenerative properties that can repair cartilage damage, lower...

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Bibliographic Details
Main Authors: Siyi Xie, Meiling Liu, Yajie Kong, Yiming Yang, Ruixue Chen, Yuzhong Wang, Shuxing Cao, Yongzhou Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
osteoarthritis
type 2 diabetes mellitus
diabetic osteoarthritis
mesenchymal stromal/stem cell-derived exosomes
microRNAs
engineered exosomes
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1549096/full
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