Interaction of Green Polymer Blend of Modified Sodium Alginate and Carboxylmethyl Cellulose Encapsulation of Turmeric Extract
Turmeric extract (tmr) loaded nanoparticles were prepared by crosslinking modified carboxylmethyl cellulose (CMC) and modified sodium alginate (SA) with calcium ions, in a high pressure homogenizer. The FTIR spectra of CMC and SA were affected by blending due to hydrogen bonding. The negative zeta p...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | International Journal of Polymer Science |
| Online Access: | http://dx.doi.org/10.1155/2013/364253 |
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| author | Sa-Ad Riyajan Janthanipa Nuim |
| author_facet | Sa-Ad Riyajan Janthanipa Nuim |
| author_sort | Sa-Ad Riyajan |
| collection | DOAJ |
| description | Turmeric extract (tmr) loaded nanoparticles were prepared by crosslinking modified carboxylmethyl cellulose (CMC) and modified sodium alginate (SA) with calcium ions, in a high pressure homogenizer. The FTIR spectra of CMC and SA were affected by blending due to hydrogen bonding. The negative zeta potential increased in magnitude with CMC content. The smallest nanoparticles were produced with a 10 : 5 SA/CMC blend. Also the release rates of the extract loading were measured, with model fits indicating that the loading level affected the release rate through nanoparticle structure. The 10 : 5 SA/CMC blend loading with tmr and pure tmr showed a good % growth inhibition of colon cancer cells which indicate that tmr in the presence of curcumin in tmr retains its anticancer activity even after being loaded into SA/CMC blend matrix. |
| format | Article |
| id | doaj-art-28cdd3f3a50041f6b5f18eea0e2a6f9c |
| institution | Kabale University |
| issn | 1687-9422 1687-9430 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Polymer Science |
| spelling | doaj-art-28cdd3f3a50041f6b5f18eea0e2a6f9c2025-02-03T06:11:16ZengWileyInternational Journal of Polymer Science1687-94221687-94302013-01-01201310.1155/2013/364253364253Interaction of Green Polymer Blend of Modified Sodium Alginate and Carboxylmethyl Cellulose Encapsulation of Turmeric ExtractSa-Ad Riyajan0Janthanipa Nuim1Department of Materials Science and Technology, Natural Product Research Center of Excellence, Faculty of Science, Prince of Songkla University, Songkhla 90112, ThailandDepartment of Materials Science and Technology, Natural Product Research Center of Excellence, Faculty of Science, Prince of Songkla University, Songkhla 90112, ThailandTurmeric extract (tmr) loaded nanoparticles were prepared by crosslinking modified carboxylmethyl cellulose (CMC) and modified sodium alginate (SA) with calcium ions, in a high pressure homogenizer. The FTIR spectra of CMC and SA were affected by blending due to hydrogen bonding. The negative zeta potential increased in magnitude with CMC content. The smallest nanoparticles were produced with a 10 : 5 SA/CMC blend. Also the release rates of the extract loading were measured, with model fits indicating that the loading level affected the release rate through nanoparticle structure. The 10 : 5 SA/CMC blend loading with tmr and pure tmr showed a good % growth inhibition of colon cancer cells which indicate that tmr in the presence of curcumin in tmr retains its anticancer activity even after being loaded into SA/CMC blend matrix.http://dx.doi.org/10.1155/2013/364253 |
| spellingShingle | Sa-Ad Riyajan Janthanipa Nuim Interaction of Green Polymer Blend of Modified Sodium Alginate and Carboxylmethyl Cellulose Encapsulation of Turmeric Extract International Journal of Polymer Science |
| title | Interaction of Green Polymer Blend of Modified Sodium Alginate and Carboxylmethyl Cellulose Encapsulation of Turmeric Extract |
| title_full | Interaction of Green Polymer Blend of Modified Sodium Alginate and Carboxylmethyl Cellulose Encapsulation of Turmeric Extract |
| title_fullStr | Interaction of Green Polymer Blend of Modified Sodium Alginate and Carboxylmethyl Cellulose Encapsulation of Turmeric Extract |
| title_full_unstemmed | Interaction of Green Polymer Blend of Modified Sodium Alginate and Carboxylmethyl Cellulose Encapsulation of Turmeric Extract |
| title_short | Interaction of Green Polymer Blend of Modified Sodium Alginate and Carboxylmethyl Cellulose Encapsulation of Turmeric Extract |
| title_sort | interaction of green polymer blend of modified sodium alginate and carboxylmethyl cellulose encapsulation of turmeric extract |
| url | http://dx.doi.org/10.1155/2013/364253 |
| work_keys_str_mv | AT saadriyajan interactionofgreenpolymerblendofmodifiedsodiumalginateandcarboxylmethylcelluloseencapsulationofturmericextract AT janthanipanuim interactionofgreenpolymerblendofmodifiedsodiumalginateandcarboxylmethylcelluloseencapsulationofturmericextract |